| Literature DB >> 30388011 |
Soobin Lim1, Dalnim Song1, Seungwon Jeon1, Youngsuk Kim1, Hyunseok Kim, Sanghee Lee2,3, Hyungdo Cho, Byung Chul Lee2,4, Sang Eun Kim2,4,3, Kimoon Kim1, Eunsung Lee1.
Abstract
A mild and practical cobalt-catalyzed defluoroborylation of fluoroarenes is presented for the first time. The method permits straightforward functionalization of fluoroarenes, with high selectivity for borylation of C-F over C-H bonds, and a tolerance for aerobic conditions. Furthermore, two-step 18F-fluorination was achieved for expanding the scope of 18F-positron emission tomography probes.Entities:
Year: 2018 PMID： 30388011 DOI： 10.1021/acs.orglett.8b03167
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005