| Literature DB >> 30387986 |
Bengt Fadeel1, Cyrill Bussy2, Sonia Merino3, Ester Vázquez3, Emmanuel Flahaut4, Florence Mouchet4, Lauris Evariste4, Laury Gauthier4, Antti J Koivisto5, Ulla Vogel5, Cristina Martín6, Lucia G Delogu7,8, Tina Buerki-Thurnherr9, Peter Wick9, Didier Beloin-Saint-Pierre9, Roland Hischier9, Marco Pelin10, Fabio Candotto Carniel10, Mauro Tretiach10, Fabrizia Cesca11, Fabio Benfenati11, Denis Scaini12, Laura Ballerini12, Kostas Kostarelos2, Maurizio Prato13,14,15, Alberto Bianco6.
Abstract
Graphene and its derivatives are heralded as "miracle" materials with manifold applications in different sectors of society from electronics to energy storage to medicine. The increasing exploitation of graphene-based materials (GBMs) necessitates a comprehensive evaluation of the potential impact of these materials on human health and the environment. Here, we discuss synthesis and characterization of GBMs as well as human and environmental hazard assessment of GBMs using in vitro and in vivo model systems with the aim to understand the properties that underlie the biological effects of these materials; not all GBMs are alike, and it is essential that we disentangle the structure-activity relationships for this class of materials.Entities:
Keywords: carbon nanomaterials; environment; exposure; graphene; hazard; life cycle assessment; safety; toxicity
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Year: 2018 PMID： 30387986 DOI： 10.1021/acsnano.8b04758
Source DB: PubMed Journal: ACS Nano ISSN： 1936-0851 Impact factor: 15.881