| Literature DB >> 30387355 |
Arihiro Iwasaki1, Takato Tadenuma1, Shimpe Sumimoto1, Ikuma Shiota1, Teruhiko Matsubara2, Yumiko Saito-Nakano3, Tomoyoshi Nozaki4, Toshinori Sato2, Kiyotake Suenaga1.
Abstract
Hoshinoamides A (1) and B (2), new acyclic lipopeptides, were isolated from the marine cyanobacterium Caldora penicillata. Their structures were elucidated by spectroscopic analyses and degradation reactions. Hoshinoamides A (1) and B (2) did not exhibit any cytotoxicity against HeLa cells at 10 μM, but inhibited the in vitro growth of the malarial parasite Plasmodium falciparum (IC50 = 0.52 and 1.0 μM, respectively).Entities:
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Year: 2018 PMID： 30387355 DOI： 10.1021/acs.jnatprod.8b00643
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050