Literature DB >> 30383993

Surgical Revascularization in Chronic Limb-threatening Ischemia in Diabetic Patients.

Cristina Neagu, Alexandra Buzea, Alexandra Agache, Dragoş Georgescu, Traian Pătraşcu.   

Abstract

Introduction: Diabetes mellitus is one of the chronic diseases that showed a steady increase in the number of patients in the last decades. After the diagnosis of diabetes mellitus, evolution towards limb amputation goes, step by step, through neuropathy, leg ulcers and infection appearance. The existence of diabetic arteriopathy prevents ulcer's healing due to the limb's ischemic status. By restoring arterial flow in the lower extremity, we solve the most important cause for diabetic foot ulcers, namely ischemia. Material and
Methods: In the Surgery Clinic of Dr I Cantacuzino Clinical Hospital, Surgical Repair of Diabetic Foot Compartment, the first revascularizations were made approx 5 years ago. During this time we have made constant efforts to lower the number of major amputations by diversifying the interventions dedicated almost exclusively to patients with ulcer of the diabetic foot.
Results: The number of major amputations is lower after revascularisation and we have obtained complete ulcer's healing and a functional extremity. We have 80 patients in observation who underwent revasculariosation surgery, ages between 40 and 75 years, 46 men and 34 women. All of them were diabetic patients with critical ischemia and various associated comorbidities: 24% arterial hypertension, 14% polineuropathy, 12% dyslipidemia. The complications occured in the first year of follow-up were 14 cases of graft thrombosis and only 6 cases of major amputation. Conclusions: Before tempting any type of amputation, major or minor, after local infection control by treatment, debridement or dressings, and after vascular evaluation, it is essential to restore arterial flow. Celsius.

Entities:  

Keywords:  amputation; arteriopathy; criticallimbischemia; diabetesmellitus; diabeticfoot

Mesh:

Year:  2018        PMID: 30383993     DOI: 10.21614/chirurgia.113.5.668

Source DB:  PubMed          Journal:  Chirurgia (Bucur)        ISSN: 1221-9118


  2 in total

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Authors:  Qiongyao Guo; Zhouyue Li; Hua Chen
Journal:  Comput Math Methods Med       Date:  2022-05-27       Impact factor: 2.809

2.  Comparison of the impact of autologous cell therapy and conservative standard treatment on tissue oxygen supply and course of the diabetic foot in patients with chronic limb-threatening ischemia: A randomized controlled trial.

Authors:  Michal Dubský; Jitka Husáková; Robert Bem; Alexandra Jirkovská; Andrea Němcová; Vladimíra Fejfarová; Karol Sutoris; Michal Kahle; Edward B Jude
Journal:  Front Endocrinol (Lausanne)       Date:  2022-08-29       Impact factor: 6.055

  2 in total

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