| Literature DB >> 3038235 |
M Gregoire, I Orly, L M Kerebel, B Kerebel.
Abstract
The effect of synthetic granular hydroxyapatite (HAP) on cultured fibroblastic cells (L929, human bone and gingiva cells) was studied. Phagocytosis of HAP particles and resulting morphological cell changes were demonstrated by microscopic examinations. Cell counts and [3H]thymidine uptake indicated significant increases in cell proliferation and DNA synthesis. These results could account for some of the alterations of the fibroblast behavior induced by changes in intracellular levels of calcium ions released from the material.Entities:
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Year: 1987 PMID： 3038235 DOI： 10.1111/j.1768-322x.1987.tb00538.x
Source DB: PubMed Journal: Biol Cell ISSN： 0248-4900 Impact factor: 4.458