| Literature DB >> 30381073 |
Kumud Joshi1,2, Bhaskar Mazumder2, Pronobesh Chattopadhyay1, Nilutpal Sharma Bora1,2, Danswrang Goyary1, Sanjeev Karmakar1.
Abstract
Graphene in nano form has proven to be one of the most remarkable materials. It has a single atom thick molecular structure and it possesses exceptional physical strength, electrical and electronic properties. Applications of the Graphene Family of Nanomaterials (GFNs) in different fields of therapy have emerged, including for targeted drug delivery in cancer, gene delivery, antimicrobial therapy, tissue engineering and more recently in more diseases including HIV. This review seeks to analyze current advances of potential applications of graphene and its family of nano-materials for drug delivery and other major biomedical purposes. Moreover, safety and toxicity are the major roadblocks preventing the use of GFNs in therapeutics. This review intends to analyze the safety and biocompatibility of GFNs along with the discussion on the latest techniques developed for toxicity reduction and biocompatibility enhancement of GFNs. This review seeks to evaluate how GFNs in future will serve as biocompatible and useful biomaterials in therapeutics. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: Graphene; antimicrobial therapy; drug delivery; graphene biocompatibility; graphene nanoplatelets; graphene nanoribbons; tissue engineering.
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Year: 2019 PMID: 30381073 DOI: 10.2174/1567201815666181031162208
Source DB: PubMed Journal: Curr Drug Deliv ISSN: 1567-2018 Impact factor: 2.565