Philippe C Dixon1, Sharleen Gomes2, Richard A Preuss3, Shawn M Robbins4. 1. Bouvé College of Health Sciences, Northeastern University, Boston, USA; Centre for Interdisciplinary Research in Rehabilitation, Constance Lethbridge Rehabilitation Centre, Montreal, Canada; School of Physical and Occupational Therapy, McGill University, Montreal, Canada. Electronic address: phil.dixon@mail.mcgill.ca. 2. Centre for Interdisciplinary Research in Rehabilitation, Constance Lethbridge Rehabilitation Centre, Montreal, Canada; School of Physical and Occupational Therapy, McGill University, Montreal, Canada. Electronic address: sharleen.gomes@mail.mcgill.ca. 3. Centre for Interdisciplinary Research in Rehabilitation, Constance Lethbridge Rehabilitation Centre, Montreal, Canada; School of Physical and Occupational Therapy, McGill University, Montreal, Canada. Electronic address: richard.preuss@mcgill.ca. 4. Centre for Interdisciplinary Research in Rehabilitation, Constance Lethbridge Rehabilitation Centre, Montreal, Canada; School of Physical and Occupational Therapy, McGill University, Montreal, Canada. Electronic address: shawn.robbins@mcgill.ca.
Abstract
BACKGROUND: Patients with knee osteoarthritis often present with varus thrust and muscular co-contraction during gait. It is unclear if these adaptations are related. The objective was to examine the relationship between muscle co-contraction and varus thrust during gait in patients with knee osteoarthritis and to determine if these relationships are modulated by disease severity or history of knee ligament rupture. METHODS: Participants (n = 42, 23 women, mean age 58 years) with knee osteoarthritis completed gait trials at self-selected speeds. Varus thrust was measured with an eight camera motion capture system sampled at 100 Hz. Co-contraction ratios were measured with surface electromyography sampled at 2000 Hz over the quadriceps, hamstrings, and gastrocnemius. Disease severity was measured on radiographs and history of anterior cruciate ligament rupture was confirmed on magnetic resonance imaging. Linear regression analyses examined the relationship between varus thrust and co-contraction ratios after controlling for radiographic disease severity and history of anterior cruciate ligament rupture. FINDINGS: Higher vastus lateralis-lateral hamstring (b = 0.081, P < 0.001; R2 = 0.353) and vastus medialis-medial hamstring (b = 0.063, P = 0.028; R2 = 0.168) co-contraction ratios were associated with greater varus thrust. Quadriceps-gastrocnemius co-contractions ratios were not related to varus thrust (P > 0.05). Radiographic disease severity or history of anterior cruciate ligament injury did not significantly contribute to regression models. INTERPRETATION: Greater quadriceps-hamstring co-contraction is associated with greater varus thrust in patients with knee osteoarthritis. Potential explanations include increased co-contraction may provide stability or there is a proprioceptive reflex that is independent of any stabilizing role. Research is needed to test these hypotheses.
BACKGROUND:Patients with knee osteoarthritis often present with varus thrust and muscular co-contraction during gait. It is unclear if these adaptations are related. The objective was to examine the relationship between muscle co-contraction and varus thrust during gait in patients with knee osteoarthritis and to determine if these relationships are modulated by disease severity or history of knee ligament rupture. METHODS:Participants (n = 42, 23 women, mean age 58 years) with knee osteoarthritis completed gait trials at self-selected speeds. Varus thrust was measured with an eight camera motion capture system sampled at 100 Hz. Co-contraction ratios were measured with surface electromyography sampled at 2000 Hz over the quadriceps, hamstrings, and gastrocnemius. Disease severity was measured on radiographs and history of anterior cruciate ligament rupture was confirmed on magnetic resonance imaging. Linear regression analyses examined the relationship between varus thrust and co-contraction ratios after controlling for radiographic disease severity and history of anterior cruciate ligament rupture. FINDINGS: Higher vastus lateralis-lateral hamstring (b = 0.081, P < 0.001; R2 = 0.353) and vastus medialis-medial hamstring (b = 0.063, P = 0.028; R2 = 0.168) co-contraction ratios were associated with greater varus thrust. Quadriceps-gastrocnemius co-contractions ratios were not related to varus thrust (P > 0.05). Radiographic disease severity or history of anterior cruciate ligament injury did not significantly contribute to regression models. INTERPRETATION: Greater quadriceps-hamstring co-contraction is associated with greater varus thrust in patients with knee osteoarthritis. Potential explanations include increased co-contraction may provide stability or there is a proprioceptive reflex that is independent of any stabilizing role. Research is needed to test these hypotheses.
Authors: M T Murphy; N Wang; D T Felson; M C Nevitt; C E Lewis; L Frey-Law; A Guermazi; N A Segal Journal: Osteoarthritis Cartilage Date: 2022-03-18 Impact factor: 7.507