Literature DB >> 30379991

New horizons in hepatitis B and C in the older adult.

Linda Kemp1, Kathleen E Clare1, Paul N Brennan1, John F Dillon1.   

Abstract

Hepatitis C (HCV) and hepatitis B (HBV), are blood-borne viruses that can cause acute hepatitis; but are clinically relevant because chronic infection is associated with development of cirrhosis and hepatocellular carcinoma. Both these viruses are becoming more common in the older population, due to the ageing of generations exposed to the risk factors associated with infection; intravenous drug use, multiple sexual partners and men who have sex with men. This review will cover the natural history and epidemiology of these infections as well as the revolution in drug therapy that now allows cure of HCV infection and complete control of HBV infection.

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Year:  2019        PMID: 30379991     DOI: 10.1093/ageing/afy170

Source DB:  PubMed          Journal:  Age Ageing        ISSN: 0002-0729            Impact factor:   10.668


  1 in total

1.  Ca2+/Calmodulin-Dependent Protein Kinase II Inhibits Hepatitis B Virus Replication from cccDNA via AMPK Activation and AKT/mTOR Suppression.

Authors:  Jumi Kim; Hyeonjoong Kwon; Fadia Kalsoom; Muhammad Azhar Sajjad; Hyun Woong Lee; Jin Hong Lim; Jaesung Jung; Yong-Joon Chwae; Sun Park; Ho-Joon Shin; Kyongmin Kim
Journal:  Microorganisms       Date:  2022-02-23
  1 in total

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