| Literature DB >> 30377696 |
Pei-Qi Hao1, Xin-Yu Zhang1, Hui Guo1,2, Yang Yang1, Shu An1, Ying Liu1, Xiao-Xi Guo1, Tian-Rui Xu3, Qian Hao4.
Abstract
Son of sevenless homolog 1 (SOS1) protein is a ubiquitously expressed adapter. As a key protein in intracellular signaling, SOS1 plays an important role in many signal transduction pathways, such as Ras and Rac signaling pathways. The abnormal expression or mutation of SOS1 is closely related to clinical diseases. In this article, we review research progress on SOS1 functions and its roles in physiology and pathophysiology.Entities:
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Year: 2018 PMID： 30377696
Source DB: PubMed Journal: Sheng Li Xue Bao ISSN： 0371-0874