| Literature DB >> 30377364 |
Simone Codeluppi1,2,3, Lars E Borm4,5, Amit Zeisel4,5,6, Gioele La Manno4,5, Josina A van Lunteren7, Camilla I Svensson8, Sten Linnarsson9,10.
Abstract
Global efforts to create a molecular census of the brain using single-cell transcriptomics are producing a large catalog of molecularly defined cell types. However, spatial information is lacking and new methods are needed to map a large number of cell type-specific markers simultaneously on large tissue areas. Here, we describe a cyclic single-molecule fluorescence in situ hybridization methodology and define the cellular organization of the somatosensory cortex.Mesh：
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Year: 2018 PMID： 30377364 DOI： 10.1038/s41592-018-0175-z
Source DB: PubMed Journal: Nat Methods ISSN： 1548-7091 Impact factor: 28.547