Yunneng Cui1, Weichao Yang1, Xiaochao Fang1, Yinxia Zhao2,3, Xiaodong Zhang2,3. 1. Department of Radiology, Foshan Maternity and Children's Healthcare Hospital Affiliated to Southern Medical University, Foshan 528000, China. 2. Department of Radiology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China. 3. Academy of Orthopedics of Guangdong Province, Guangzhou 510630, China.
Abstract
OBJECTIVE: To investigate changes over time in the shape and signal intensity of high intensity zone (HIZ) in the lumbar intervertebral discs on magnetic resonance images in patients with low back pain. METHODS: The imaging data were collected from 27 patients with low back pain, who underwent lumbar magnetic resonance (MR) imaging examinations that identified HIZ lesions and received follow-up MR examinations at least 1.5 years later over the period from January 2009 to January 2017. The initial and follow-up MR T2WI images of the patients were read by two experienced radiologists to categorize the changes in the shape of the HIZ lesions into enlarged, unchanged, shrunk, and disappeared. The volume and signal/cerebrospinal fluid signal intensity (T2/CSF) ratio of the HIZ were measured on sagittal MR images using ImageJ software. RESULTS: Of the 43 HIZ lesions found in the initial examinations, 22 (51.2%) remained unchanged in the follow-up examinations, 10 (21.3%) were enlarged, 9 (20.9%) shrank, and 2 (23.3%) disappeared. The follow-up examinations revealed 4 new HIZ lesions in the intervertebral discs. The volumes of these lesions did not vary significantly in the follow-up examinations (P=0.653), but the T2/CSF ratio was significantly higher in the follow-up than in the initial examinations (P=0.043). CONCLUSIONS: After observation for an average of 3 years and 3 months, most of the HIZ lesions in the lumbar intervertebral discs of the patients with low back pain remained stable in shape, but their signal intensity on MR images increased.
OBJECTIVE: To investigate changes over time in the shape and signal intensity of high intensity zone (HIZ) in the lumbar intervertebral discs on magnetic resonance images in patients with low back pain. METHODS: The imaging data were collected from 27 patients with low back pain, who underwent lumbar magnetic resonance (MR) imaging examinations that identified HIZ lesions and received follow-up MR examinations at least 1.5 years later over the period from January 2009 to January 2017. The initial and follow-up MR T2WI images of the patients were read by two experienced radiologists to categorize the changes in the shape of the HIZ lesions into enlarged, unchanged, shrunk, and disappeared. The volume and signal/cerebrospinal fluid signal intensity (T2/CSF) ratio of the HIZ were measured on sagittal MR images using ImageJ software. RESULTS: Of the 43 HIZ lesions found in the initial examinations, 22 (51.2%) remained unchanged in the follow-up examinations, 10 (21.3%) were enlarged, 9 (20.9%) shrank, and 2 (23.3%) disappeared. The follow-up examinations revealed 4 new HIZ lesions in the intervertebral discs. The volumes of these lesions did not vary significantly in the follow-up examinations (P=0.653), but the T2/CSF ratio was significantly higher in the follow-up than in the initial examinations (P=0.043). CONCLUSIONS: After observation for an average of 3 years and 3 months, most of the HIZ lesions in the lumbar intervertebral discs of the patients with low back pain remained stable in shape, but their signal intensity on MR images increased.
Entities:
Keywords:
high intensity zone; intervertebral disc degeneration; magnetic resonance imaging
Authors: Philip K Louie; Alejandro A Espinoza Orías; Louis F Fogg; Mark LaBelle; Howard S An; Gunnar B J Andersson Journal: Spine (Phila Pa 1976) Date: 2018-10-01 Impact factor: 3.468
Authors: W Brinjikji; F E Diehn; J G Jarvik; C M Carr; D F Kallmes; M H Murad; P H Luetmer Journal: AJNR Am J Neuroradiol Date: 2015-09-10 Impact factor: 3.825