Literature DB >> 30375105

A retrospective observational study of acquired subglottic stenosis using low-pressure, high-volume cuffed endotracheal tubes.

David Greaney1, John Russell2, Ian Dawkins3, Martina Healy1.   

Abstract

INTRODUCTION: The safety of cuffed endotracheal tubes in the neonatal and critically ill pediatric population continues to be questioned due to the theoretical risk of acquired subglottic stenosis. The incidence of acquired subglottic stenosis in the high-risk mixed surgical and medical critically ill pediatric cohort using high-volume, low-pressure cuffed endotracheal tube policy has not yet been described. The aim of our study was to describe and evaluate the use and complication rate of cuffed ETT's in our unit over a 5-year period.
METHODS: We defined clinically significant subglottic stenosis as a positive stenotic finding of endotracheal tube-related pathology on a microlaryngoscopy within 6 months of invasive ventilation. All patients admitted through our pediatric critical care unit from January 10, 2012 to January 25, 2017 were matched against our theater management system database for the same period. We reviewed all matching patients' baseline demographics, comorbidities, intubation/endotracheal tube history, and subsequent surgical management.
RESULTS: Of 5309 pediatric critical care unit admissions (61% ventilated) and 1251 microlaryngoscopies, 23 children had endoscopic findings of clinically significant endotracheal tube-related pathology, reflecting 0.68% of all intubated patients. Eight patients developed acquired subglottic stenosis. All those requiring major surgical correction were ex-premature neonates initially intubated with uncuffed tubes in an external neonatal intensive care. No patient initially intubated with a cuffed endotracheal tube developed subglottic stenosis requiring surgical correction.
CONCLUSION: We report no single case of acquired subglottic stenosis in our cohort that required major surgical correction from a cuffed endotracheal tube during a 5-year period. The introduction of a policy of appropriate placement and maintenance of low-pressure, high-volume cuffed endotracheal tubes in the pediatric critical care unit was not associated with an increased rate of endotracheal tube-related subglottic trauma.
© 2018 John Wiley & Sons Ltd.

Entities:  

Keywords:  acquired subglottic stenosis; endotracheal; intensive care units; intubation; pediatric

Mesh:

Year:  2018        PMID: 30375105     DOI: 10.1111/pan.13519

Source DB:  PubMed          Journal:  Paediatr Anaesth        ISSN: 1155-5645            Impact factor:   2.556


  2 in total

Review 1.  Cuffed versus uncuffed endotracheal tubes for neonates.

Authors:  Vedanta Dariya; Luca Moresco; Matteo Bruschettini; Luc P Brion
Journal:  Cochrane Database Syst Rev       Date:  2022-01-24

2.  Incidence of Post-extubation Stridor in Infants With Cuffed vs. Uncuffed Endotracheal Tube: A Retrospective Cohort Analysis.

Authors:  Katharina Bibl; Lena Pracher; Erik Küng; Michael Wagner; Imme Roesner; Angelika Berger; Michael Hermon; Tobias Werther
Journal:  Front Pediatr       Date:  2022-05-11       Impact factor: 3.569

  2 in total

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