Literature DB >> 30375104

Cardioversion of atrial fibrillation in obese patients: Results from the Cardioversion-BMI randomized controlled trial.

Aleksandr Voskoboinik1,2,3,4, Jeremy Moskovitch1, George Plunkett5, Jason Bloom1, Geoffrey Wong3, Chrishan Nalliah3, Sandeep Prabhu1,2,3,4, Hariharan Sugumar1,2,3,4, Ramanathan Paramasweran3, Alex McLellan1,2,3, Liang-Han Ling1,2,3, Cheng-Yee Goh6, Samer Noaman1,6, Himawan Fernando1, Michael Wong1,2,3,6, Andrew J Taylor1,2,3, Jonathan M Kalman1,2,3,7, Peter M Kistler1,2,3,4,7.   

Abstract

AIMS: Obesity is associated with higher electrical cardioversion (ECV) failure in persistent atrial fibrillation (PeAF). For ease-of-use, many centers prefer patches over paddles. We assessed the optimum modality and shock vector, as well as the safety and efficacy of the Manual Pressure Augmentation (MPA) technique.
METHODS: Patients with obesity (BMI ≥ 30) and PeAF undergoing ECV using a biphasic defibrillator were randomized into one of four arms by modality (adhesive patches or handheld paddles) and shock vector (anteroposterior [AP] or anteroapical [AA]). If the first two shocks (100 and 200 J) failed, then patients received a 200-J shock using the alternative modality (patch or paddle). Shock vector remained unchanged. In an observational substudy, 20 patients with BMI of 35 or more, and who failed ECV at 200 J using both patches/paddles underwent a trial of MPA.
RESULTS: In total, 125 patients were randomized between July 2016 and March 2018. First or second shock success was 43 of 63 (68.2%) for patches and 56 of 62 (90.3%) for paddles (P = 0.002). There were 20 crossovers from patches to paddles (12 of 20 third shock success with paddles) and six crossovers from paddles to patches (three of six third shock success with patches). Paddles successfully cardioverted 68 of 82 patients compared with 46 of 69 using patches (82.9% vs 66.7%; P = 0.02). Shock vector did not influence first or second shock success rates (82.0% AP vs 76.6% AA; P = 0.46). MPA was successful in 16 of 20 (80%) who failed in both (patches/paddles), with 360 J required in six of seven cases.
CONCLUSION: Routine use of adhesive patches at 200 J is inadequate in obesity. Strategies that improve success include the use of paddles, MPA, and escalation to 360 J.
© 2018 Wiley Periodicals, Inc.

Entities:  

Keywords:  atrial fibrillation; direct current cardioversion; left atrium; obesity; transthoracic impedance

Mesh:

Year:  2018        PMID: 30375104     DOI: 10.1111/jce.13786

Source DB:  PubMed          Journal:  J Cardiovasc Electrophysiol        ISSN: 1045-3873


  6 in total

1.  Efficacy of Electrical Cardioversion in Relation to Occurrence and Type of Functional Mitral Regurgitation in Patients with Atrial Fibrillation.

Authors:  Konrad Klocek; Katarzyna Klimek; Michał Tworek; Karolina Wrona-Kolasa; Małgorzata Cichoń; Maciej Wybraniec; Katarzyna Mizia-Stec
Journal:  J Clin Med       Date:  2022-04-07       Impact factor: 4.964

2.  Disease-treatment interactions in the management of patients with obesity and diabetes who have atrial fibrillation: the potential mediating influence of epicardial adipose tissue.

Authors:  Milton Packer
Journal:  Cardiovasc Diabetol       Date:  2019-09-24       Impact factor: 9.951

3.  Ex vivo evaluation of personal protective equipment in hands-on defibrillation.

Authors:  Andrew F Stephens; Michael Šeman; Ziad Nehme; Aleksandr Voskoboinik; Karen Smith; Shaun D Gregory; Dion Stub
Journal:  Resusc Plus       Date:  2022-08-03

Review 4.  [Cardiac arrest under special circumstances].

Authors:  Carsten Lott; Anatolij Truhlář; Anette Alfonzo; Alessandro Barelli; Violeta González-Salvado; Jochen Hinkelbein; Jerry P Nolan; Peter Paal; Gavin D Perkins; Karl-Christian Thies; Joyce Yeung; David A Zideman; Jasmeet Soar
Journal:  Notf Rett Med       Date:  2021-06-10       Impact factor: 0.826

Review 5.  Heart failure with preserved ejection fraction based on aging and comorbidities.

Authors:  Ying Lin; Shihui Fu; Yao Yao; Yulong Li; Yali Zhao; Leiming Luo
Journal:  J Transl Med       Date:  2021-07-06       Impact factor: 5.531

6.  External Cardioversion-Defibrillation with Pushing Down on the Chest Wall to Increase the Success Rate in Obese Patients.

Authors:  Ming-Lon Young; Eric J Exelbert; Todd Roth; Lance Cohen; John Cogan
Journal:  Am J Case Rep       Date:  2020-11-16
  6 in total

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