| Literature DB >> 30373790 |
Perrine Parize1, Anne-Claire Mamez2, Dea Garcia-Hermoso3, Valérie Dumaine4, Sylvain Poirée5, Catherine Kauffmann-Lacroix6, Vincent Jullien7, Olivier Lortholary2,3, Fanny Lanternier2,3.
Abstract
Osteoarticular mucormycosis cases are quite rare and challenging infections that are mostly due to direct inoculation during traumatic injury among immunocompetent patients. Classic management includes a combination of aggressive surgical debridement, which may lead to amputation, and long-term systemic liposomal amphotericin B therapy. This article describes the successful treatment of Saksenaea sp. osteomyelitis in a patient with diabetes mellitus, using a combination of systemic antifungal therapy and conservative surgery with insertion of amphotericin-impregnated cement beads.Entities:
Keywords: Mucoraleszzm321990; amphotericin B; antifungal agents; osteomyelitis
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Year: 2018 PMID: 30373790 PMCID: PMC6325185 DOI: 10.1128/AAC.01006-18
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191