| Literature DB >> 30373382 |
Qixiao Zhai1,2,3, Saisai Feng1,2, Narbad Arjan3,4, Wei Chen1,2,5,6,7.
Abstract
Akkermansia muciniphila, a symbiotic bacterium of the mucus layer, can utilize mucin as its sole carbon, nitrogen, and energy source. As an abundant resident in the intestinal tract of humans and animals, the probiotic effects of A. muciniphila including metabolic modulation, immune regulation and gut health protection, have been widely investigated. Various diseases such as metabolic syndromes and auto-immnue diseases have been reported to be associated with the disturbance of the abundance of A. muciniphila. In this review, we describe the biological characterization of A. muciniphia, the factors that influence its colonization of the intestinal tract; and discuss the current state of our knowledge on its role in host health and disease.Entities:
Keywords: Akkermansia muciniphila; diet; host health and disease; mucin
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Year: 2018 PMID： 30373382 DOI： 10.1080/10408398.2018.1517725
Source DB: PubMed Journal: Crit Rev Food Sci Nutr ISSN： 1040-8398 Impact factor: 11.176