Literature DB >> 3037326

Functional simian virus 40 T antigen is expressed in hybrid cells having finite proliferative potential.

O M Pereira-Smith, J R Smith.   

Abstract

Simian virus 40-transformed human cells fused with other independently derived simian virus 40-transformed cells and tumor-derived cells containing activated H-ras and N-ras oncogenes yielded hybrids capable of indefinite division. Fusions with various other immortal cells yielded hybrids that had limited division potential. T antigen expressed in limited-division hybrids was functional for the induction of cellular DNA synthesis.

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Year:  1987        PMID: 3037326      PMCID: PMC365243          DOI: 10.1128/mcb.7.4.1541-1544.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


  28 in total

1.  Function of simian virus 40 gene A in transforming infection.

Authors:  P Tegtmeyer
Journal:  J Virol       Date:  1975-03       Impact factor: 5.103

2.  Initiation and maintenance of cell transformation by simian virus 40: a viral genetic property.

Authors:  G Kimura; A Itagaki
Journal:  Proc Natl Acad Sci U S A       Date:  1975-02       Impact factor: 11.205

3.  Simian virus 40 functions required for the establishment and maintenance of malignant transformation.

Authors:  R G Martin; J Y Chou
Journal:  J Virol       Date:  1975-03       Impact factor: 5.103

4.  Role of simian virus 40 gene A function in maintenance of transformation.

Authors:  J S Brugge; J S Butel
Journal:  J Virol       Date:  1975-03       Impact factor: 5.103

5.  Simian virus 40 gene A function and maintenance of transformation.

Authors:  M Osborn; K Weber
Journal:  J Virol       Date:  1975-03       Impact factor: 5.103

6.  Transformation of BALB/c-3T3 cells by tsA mutants of simian virus 40: temperature sensitivity of the transformed phenotype and retransofrmation by wild-type virus.

Authors:  W W Brockman
Journal:  J Virol       Date:  1978-03       Impact factor: 5.103

7.  Transformation of human cells by temperature-sensitive mutants of simian virus-40.

Authors:  C A Lomax; E Bradley; J Weber; P Bourgaux
Journal:  Intervirology       Date:  1978       Impact factor: 1.763

8.  Established lines of SV40-transformed human amnion cells.

Authors:  E V Gaffney; J Fogh; L Ramos; J D Loveless; H Fogh; A M Dowling
Journal:  Cancer Res       Date:  1970-06       Impact factor: 12.701

9.  Transformation of human cystinotic fibroblasts by SV40: characteristics of transformed cells with limited and unlimited growth potential.

Authors:  R G Oshima; O L Pellett; J A Robb; J A Schneider
Journal:  J Cell Physiol       Date:  1977-10       Impact factor: 6.384

10.  Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus.

Authors:  E Blasi; B J Mathieson; L Varesio; J L Cleveland; P A Borchert; U R Rapp
Journal:  Nature       Date:  1985 Dec 19-1986 Jan 1       Impact factor: 49.962

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  6 in total

1.  Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts.

Authors:  W E Wright; O M Pereira-Smith; J W Shay
Journal:  Mol Cell Biol       Date:  1989-07       Impact factor: 4.272

2.  Genetic analysis of indefinite division in human cells: identification of four complementation groups.

Authors:  O M Pereira-Smith; J R Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

3.  Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements.

Authors:  V Band; D Zajchowski; V Kulesa; R Sager
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

4.  Extended life span of human endometrial stromal cells transfected with cloned origin-defective, temperature-sensitive simian virus 40.

Authors:  C A Rinehart; J S Haskill; J S Morris; T D Butler; D G Kaufman
Journal:  J Virol       Date:  1991-03       Impact factor: 5.103

5.  Characterization of human vascular smooth muscle cells transformed by the early genetic region of SV40 virus.

Authors:  A Legrand; P Greenspan; M L Nagpal; S A Nachtigal; M Nachtigal
Journal:  Am J Pathol       Date:  1991-09       Impact factor: 4.307

Review 6.  Toward a molecular understanding of human breast cancer: a hypothesis.

Authors:  J W Shay; W E Wright; H Werbin
Journal:  Breast Cancer Res Treat       Date:  1993       Impact factor: 4.872

  6 in total

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