| Literature DB >> 3037326 |
Abstract
Simian virus 40-transformed human cells fused with other independently derived simian virus 40-transformed cells and tumor-derived cells containing activated H-ras and N-ras oncogenes yielded hybrids capable of indefinite division. Fusions with various other immortal cells yielded hybrids that had limited division potential. T antigen expressed in limited-division hybrids was functional for the induction of cellular DNA synthesis.Entities:
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Year: 1987 PMID: 3037326 PMCID: PMC365243 DOI: 10.1128/mcb.7.4.1541-1544.1987
Source DB: PubMed Journal: Mol Cell Biol ISSN: 0270-7306 Impact factor: 4.272