| Literature DB >> 30370905 |
Wei Qi Lim1, Soo Zeng Fiona Phua, Hongzhong Chen, Yanli Zhao.
Abstract
A redox-responsive supramolecular nanocarrier was constructed from the self-assembly of spermine modified cyclodextrin and oxaliplatin prodrug. The nanocarrier could preferentially accumulate in polyamine transporter over-expressing HCT116 cells, releasing drugs under a reducing intracellular environment to maximize anticancer treatment.Entities:
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Year: 2018 PMID: 30370905 DOI: 10.1039/c8cc07858k
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222