Literature DB >> 30369963

Sociogenomics in the 21st Century: An Introduction to the History and Potential of Genetically-informed Social Science.

David B Braudt1,2.   

Abstract

This article reviews research at the intersection of genetics and sociology and provides an introduction to the current data, methods, and theories used in sociogenomic research. To accomplish this, I review behavioral genetics models, candidate gene analysis, genome-wide complex trait analysis, and the use of polygenic scores (sometimes referred to as polygenic risk scores) in the study of complex human behaviors and traits. The information provided is meant to equip readers with the necessary tools to: (1) understand the methodology employed by each type of analysis, (2) intelligently interpret findings from sociogenomic research, and (3) understand the importance of sociologists in the ever-growing field of sociogenomics. To unify these three tasks, I rely on various examples from recent sociogenomic analyses of educational attainment focusing on social stratification and inequality.

Entities:  

Keywords:  Genetics; Genome-wide; Heritability; Inequality; Polygenic Score; Social Stratification; Sociogenomics

Year:  2018        PMID: 30369963      PMCID: PMC6201284          DOI: 10.1111/soc4.12626

Source DB:  PubMed          Journal:  Sociol Compass        ISSN: 1751-9020


  59 in total

1.  Principal components analysis corrects for stratification in genome-wide association studies.

Authors:  Alkes L Price; Nick J Patterson; Robert M Plenge; Michael E Weinblatt; Nancy A Shadick; David Reich
Journal:  Nat Genet       Date:  2006-07-23       Impact factor: 38.330

2.  Spurious genetic associations.

Authors:  Patrick F Sullivan
Journal:  Biol Psychiatry       Date:  2007-03-08       Impact factor: 13.382

3.  Molecular genetics and subjective well-being.

Authors:  Cornelius A Rietveld; David Cesarini; Daniel J Benjamin; Philipp D Koellinger; Jan-Emmanuel De Neve; Henning Tiemeier; Magnus Johannesson; Patrik K E Magnusson; Nancy L Pedersen; Robert F Krueger; Meike Bartels
Journal:  Proc Natl Acad Sci U S A       Date:  2013-05-24       Impact factor: 11.205

4.  Editorial policy on candidate gene association and candidate gene-by-environment interaction studies of complex traits.

Authors:  John K Hewitt
Journal:  Behav Genet       Date:  2011-09-18       Impact factor: 2.805

5.  Meta-analysis of the heritability of human traits based on fifty years of twin studies.

Authors:  Tinca J C Polderman; Beben Benyamin; Christiaan A de Leeuw; Patrick F Sullivan; Arjen van Bochoven; Peter M Visscher; Danielle Posthuma
Journal:  Nat Genet       Date:  2015-05-18       Impact factor: 38.330

6.  Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation.

Authors:  Jianjun Gao; Lea K Davis; Amy B Hart; Sandra Sanchez-Roige; Lide Han; John T Cacioppo; Abraham A Palmer
Journal:  Neuropsychopharmacology       Date:  2016-09-15       Impact factor: 7.853

7.  Top 10 Replicated Findings From Behavioral Genetics.

Authors:  Robert Plomin; John C DeFries; Valerie S Knopik; Jenae M Neiderhiser
Journal:  Perspect Psychol Sci       Date:  2016-01

8.  A genome-wide approach to children's aggressive behavior: The EAGLE consortium.

Authors:  Irene Pappa; Beate St Pourcain; Kelly Benke; Alana Cavadino; Christian Hakulinen; Michel G Nivard; Ilja M Nolte; Carla M T Tiesler; Marian J Bakermans-Kranenburg; Gareth E Davies; David M Evans; Marie-Claude Geoffroy; Harald Grallert; Maria M Groen-Blokhuis; James J Hudziak; John P Kemp; Liisa Keltikangas-Järvinen; George McMahon; Viara R Mileva-Seitz; Ehsan Motazedi; Christine Power; Olli T Raitakari; Susan M Ring; Fernando Rivadeneira; Alina Rodriguez; Paul A Scheet; Ilkka Seppälä; Harold Snieder; Marie Standl; Elisabeth Thiering; Nicholas J Timpson; René Veenstra; Fleur P Velders; Andrew J O Whitehouse; George Davey Smith; Joachim Heinrich; Elina Hypponen; Terho Lehtimäki; Christel M Middeldorp; Albertine J Oldehinkel; Craig E Pennell; Dorret I Boomsma; Henning Tiemeier
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2015-06-18       Impact factor: 3.568

9.  Genome-wide analyses of borderline personality features.

Authors:  G H Lubke; C Laurin; N Amin; J J Hottenga; G Willemsen; G van Grootheest; A Abdellaoui; L C Karssen; B A Oostra; C M van Duijn; B W J H Penninx; D I Boomsma
Journal:  Mol Psychiatry       Date:  2013-08-27       Impact factor: 15.992

10.  Finding the missing heritability in pediatric obesity: the contribution of genome-wide complex trait analysis.

Authors:  C H Llewellyn; M Trzaskowski; R Plomin; J Wardle
Journal:  Int J Obes (Lond)       Date:  2013-03-26       Impact factor: 5.095

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  2 in total

1.  Disentangling Social-Genetic From Rearing-Environment Effects for Alcohol Use Disorder Using Swedish National Data.

Authors:  Jessica E Salvatore; Sara Larsson Lönn; Jan Sundquist; Kristina Sundquist; Kenneth S Kendler
Journal:  Psychol Sci       Date:  2020-08-20

2.  "Quiet is the New Loud": The Biosociology Debate's Absent Voices.

Authors:  Anja Maria Steinsland Ariansen
Journal:  Am Sociol       Date:  2021-06-03
  2 in total

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