M Matthaei1,2, B Bachmann3, D Hos3,4, S Siebelmann3, F Schaub3, C Cursiefen3,4. 1. Zentrum für Augenheilkunde, Universität zu Köln, Kerpener Str. 62, 50924, Köln, Deutschland. mario.matthaei@uk-koeln.de. 2. Zentrum für Molekulare Medizin Köln (ZMMK), Universität zu Köln, Köln, Deutschland. mario.matthaei@uk-koeln.de. 3. Zentrum für Augenheilkunde, Universität zu Köln, Kerpener Str. 62, 50924, Köln, Deutschland. 4. Zentrum für Molekulare Medizin Köln (ZMMK), Universität zu Köln, Köln, Deutschland.
Abstract
BACKGROUND: Keratoprosthetics refer to the replacement of human corneal tissue with an artificially produced exchange product. The most widely implanted keratoprosthesis worldwide is the Boston Type I Keratoprosthesis (BI-KPro, Massachusetts Eye and Ear Infirmary, Boston, MA, USA). METHODS: This video article demonstrates the surgical technique of BI-KPro implantation as routinely performed at this institution. In addition, an overview of the surgical indications, patient consent, anesthesia and positioning, postoperative treatment and complications as well as the evidence of the technique is provided in the article based on experience with 31 BI-KPro implantations. RESULTS: The indications for BI-KPro primarily include patients in a high-risk keratoplasty setting particularly after repeatedly failed keratoplasty. A thorough patient examination and assessment of the indications as well as detailed disclosure of information to the patient about the individual prognosis, the risk profile, the postoperative therapy and follow-up enable a positive postoperative result. CONCLUSION: The BI-KPro provides an established and relatively standardized option for surgical treatment of eyes in a high-risk keratoplasty setting. Patients should be preoperatively informed with respect to the individual prognosis, complication profile and life-long follow-up.
BACKGROUND: Keratoprosthetics refer to the replacement of human corneal tissue with an artificially produced exchange product. The most widely implanted keratoprosthesis worldwide is the Boston Type I Keratoprosthesis (BI-KPro, Massachusetts Eye and Ear Infirmary, Boston, MA, USA). METHODS: This video article demonstrates the surgical technique of BI-KPro implantation as routinely performed at this institution. In addition, an overview of the surgical indications, patient consent, anesthesia and positioning, postoperative treatment and complications as well as the evidence of the technique is provided in the article based on experience with 31 BI-KPro implantations. RESULTS: The indications for BI-KPro primarily include patients in a high-risk keratoplasty setting particularly after repeatedly failed keratoplasty. A thorough patient examination and assessment of the indications as well as detailed disclosure of information to the patient about the individual prognosis, the risk profile, the postoperative therapy and follow-up enable a positive postoperative result. CONCLUSION: The BI-KPro provides an established and relatively standardized option for surgical treatment of eyes in a high-risk keratoplasty setting. Patients should be preoperatively informed with respect to the individual prognosis, complication profile and life-long follow-up.
Authors: Sebastian Siebelmann; Philipp Steven; Deniz Hos; Gereon Hüttmann; Eva Lankenau; Björn Bachmann; Claus Cursiefen Journal: J Biomed Opt Date: 2016-01 Impact factor: 3.170
Authors: Friederike Schaub; Björn O Bachmann; Orang Seyeddain; Sarah Moussa; Herbert A Reitsamer; Claus Cursiefen Journal: Klin Monbl Augenheilkd Date: 2017-06-06 Impact factor: 0.700
Authors: Gábor Tóth; Franziska Bucher; Sebastian Siebelmann; Björn Bachmann; Manuel Hermann; Nóra Szentmáry; Zoltán Zsolt Nagy; Claus Cursiefen Journal: Cornea Date: 2016-06 Impact factor: 2.651
Authors: Hall F Chew; Brandon D Ayres; Kristin M Hammersmith; Christopher J Rapuano; Peter R Laibson; Jonathan S Myers; Ya-Ping Jin; Elisabeth J Cohen Journal: Cornea Date: 2009-10 Impact factor: 2.651