| Literature DB >> 30366621 |
Ximena Escalera-Fanjul1, Héctor Quezada2, Lina Riego-Ruiz3, Alicia González4.
Abstract
Studies on the fate of Saccharomyces cerevisiae paralogous gene pairs that arose through a whole-genome duplication event have shown diversification of retained duplicated genes. Paralogous functional specialization often results in improved function and/or novel function that could contribute to the adaptation of the organism to a new lifestyle. Here, we analyze and discuss particular case studies of paralogous functional diversification that could have played a role in the acquisition of yeast fermentative metabolism.Entities:
Keywords: Saccharomyces cerevisiae; fermentative metabolism; functional diversification; paralogous genes; whole-genome duplication
Mesh:
Year: 2018 PMID: 30366621 DOI: 10.1016/j.tig.2018.09.008
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639