Literature DB >> 30364809

Risk Factors for Adjacent Fractures After Cement-Augmented Thoracolumbar Pedicle Screw Instrumentation.

Falko Schwarz1, Michaela Burckhart1, Aaron Lawson McLean1, Rolf Kalff1, Albrecht Waschke1.   

Abstract

BACKGROUND: The aim of our study was to identify factors that influence the occurrence of adjacent fractures in patients with cement-augmented pedicle screw instrumentation.
METHODS: Data were retrospectively collected from medical charts and operative reports for every surgery in which cement-augmented instrumentation was used in our hospital of 4 consecutive years. A total of 93 operations were included and examined for gender, age, T-score, number of fused segments, number of implanted screws, broken screws, loosening of screws, leakage and distribution pattern of cement, pre- and postoperative kyphosis angle, revision surgery and adjacent fractures in follow-up. Categorical data were compared using the χ2 test or by Fisher's exact test, as appropriate. Continuous variables conforming to a normal distribution were compared using Student's t test. Otherwise the Mann-Whitney U test was applied. A P-value of <.05 was considered statistically significant. A trend was defined as a P < .2.
RESULTS: The mean age was 68.1 years with a mean T-score of -3.12. Nineteen adjacent fractures occurred during follow-up and the median follow-up was 12 months (range, 1-27). Patients showed a higher risk for adjacent fractures following revision surgery (P = .016). Most fractures occurred superior to the instrumented level (P = .013) and in the first 12 months. Difference of T-score between the group "no adjacent fracture" and the group "adjacent fracture" was 0.7 (P = .138). Another trends were found in greater age (P = .119) and long instrumentations (P = .199). CONCLUSIONS AND CLINICAL RELEVANCE: Revision surgeries are associated with a higher risk of adjacent fractures. In these cases, prophylactic kyphoplasty of the superior vertebra should be considered. This study is a retrospective, nonrandomized cohort/follow-up study. LEVEL OF EVIDENCE: 3.

Entities:  

Keywords:  adjacent fracture; cement-augmented; osteoporosis; pedicle screw instrumentation; spine surgery

Year:  2018        PMID: 30364809      PMCID: PMC6198631          DOI: 10.14444/5069

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  22 in total

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Journal:  Clin Neurosurg       Date:  2006

3.  The risk of new osteoporotic vertebral compression fractures in the year after percutaneous vertebroplasty.

Authors:  Maurits H J Voormolen; Paul N M Lohle; Job R Juttmann; Yolanda van der Graaf; Hendrik Fransen; Leo E H Lampmann
Journal:  J Vasc Interv Radiol       Date:  2006-01       Impact factor: 3.464

4.  Bone cement augmentation in the prevention of adjacent segment failure after multilevel adult deformity fusion.

Authors:  Friederike Lattig
Journal:  J Spinal Disord Tech       Date:  2009-08

5.  Risk factors for adjacent-segment failure following lumbar fixation with rigid instrumentation for degenerative instability.

Authors:  S Etebar; D W Cahill
Journal:  J Neurosurg       Date:  1999-04       Impact factor: 5.115

6.  Polymethylmethacrylate augmentation of pedicle screws increases the initial fixation in osteoporotic spine patients.

Authors:  Kimihiko Sawakami; Akiyoshi Yamazaki; Seiichi Ishikawa; Takui Ito; Kei Watanabe; Naoto Endo
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Review 7.  The biomechanics of pedicle screw augmentation with cement.

Authors:  Benjamin D Elder; Sheng-Fu L Lo; Christina Holmes; Courtney R Goodwin; Thomas A Kosztowski; Ioan A Lina; John E Locke; Timothy F Witham
Journal:  Spine J       Date:  2015-03-20       Impact factor: 4.166

8.  The biomechanics of 1, 2, and 3 levels of vertebral augmentation with polymethylmethacrylate in multilevel spinal segments.

Authors:  Mark Makumbi Kayanja; Richard Schlenk; Daisuke Togawa; Lisa Ferrara; Isador Lieberman
Journal:  Spine (Phila Pa 1976)       Date:  2006-04-01       Impact factor: 3.468

9.  The pedicle screw fixation with vertebroplasty augmentation in the surgical treatment of the severe osteoporotic spines.

Authors:  Mehmet Aydogan; Cagatay Ozturk; Omer Karatoprak; Mehmet Tezer; Neslihan Aksu; Azmi Hamzaoglu
Journal:  J Spinal Disord Tech       Date:  2009-08

10.  Prophylactic vertebroplasty can decrease the fracture risk of adjacent vertebrae: an in vitro cadaveric study.

Authors:  René Aquarius; Jasper Homminga; Allard Jan Frederik Hosman; Nico Verdonschot; Esther Tanck
Journal:  Med Eng Phys       Date:  2014-04-13       Impact factor: 2.242

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  2 in total

1.  Occurrence of adjacent segment fractures after surgical treatment of an osteoporotic vertebral fracture: a retrospective comparison between two different treatment methods.

Authors:  Nazeer Aboud; Niklas Eckardt; Marcel A Kamp; Christian Senft; Falko Schwarz
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Review 2.  [Postoperative imaging of the musculoskeletal system - spine].

Authors:  S Schlaeger; J S Kirschke
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  2 in total

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