| Literature DB >> 3036401 |
P K Buamah, C Cornell, A W Skillen, B M Cantwell, A L Harris.
Abstract
Serum CA-125, a glycoprotein antigen, has been measured in serum of patients with ovarian cancer, cervical cancer, or nonseminomatous germ-cell tumor of testis. Increased concentrations were found in 21 of 27 patients with epithelial ovarian cancer and two of three patients with ovarian teratoma. Changes in CA-125 concentrations in serum during chemotherapy mirrored the progress of the disease as assessed by clinical and radiological evidence. Although CA-125 provides no real asset for diagnosis, it should have value as a marker for monitoring response to chemotherapy.Entities:
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Year: 1987 PMID： 3036401
Source DB: PubMed Journal: Clin Chem ISSN： 0009-9147 Impact factor: 8.327