Literature DB >> 30363903

Safe Administration of Botulinum Toxin Type A Injections During Pregnancy: A Report of Two Cases.

Henriette Krug1, Patricia Krause1, Andreas Kupsch2, Andrea A Kühn1.   

Abstract

Local injections of botulinum toxin type A (BoNT/A) are safe and efficacious to treat focal and segmental dystonia. However, there are no adequate studies in humans regarding the safety of BoNT/A during pregnancy. Despite the fact that 25 case reports have been published on patients who received BoNT/A injections during a total of 31 pregnancies, in only 3 patients were the injections continued beyond the first trimester. We report on 2 females with cervical and segmental dystonia who received BoNT/A injections during pregnancy beyond the first trimester and gave birth to 2 healthy children.

Entities:  

Keywords:  botulinum toxin; dystonia; movement disorders; obstetrics; pregnancy

Year:  2015        PMID： 30363903      PMCID： PMC6183313          DOI： 10.1002/mdc3.12135

Source DB:  PubMed          Journal:  Mov Disord Clin Pract        ISSN： 2330-1619


  14 in total

1.  Botulinum toxin type A therapy during pregnancy.

Authors:  William J Newman; Thomas L Davis; Bimal B Padaliya; Bismal B Padaliya; Cassondra D Covington; Chandler E Gill; Anna I Abramovitch; P David Charles
Journal:  Mov Disord       Date:  2004-11       Impact factor: 10.338

Review 2.  Neurophysiological changes after intramuscular injection of botulinum toxin.

Authors:  Francisco J Palomar; Pablo Mir
Journal:  Clin Neurophysiol       Date:  2011-11-02       Impact factor: 3.708

Review 3.  Botulinum toxin for the treatment of movement disorders.

Authors:  Mary Ann Thenganatt; Stanley Fahn
Journal:  Curr Neurol Neurosci Rep       Date:  2012-08       Impact factor: 5.081

Review 4.  Botulinum toxin and pregnancy-a cautionary tale.

Authors:  J F T Li Yim; C R Weir
Journal:  Strabismus       Date:  2010-06

5.  Botulinum toxin type A therapy during pregnancy.

Authors:  Cynthia L Bodkin; Kenneth B Maurer; Zbigniew K Wszolek
Journal:  Mov Disord       Date:  2005-08       Impact factor: 10.338

6.  Botulinum toxin A during pregnancy: a survey of treating physicians.

Authors:  J C Morgan; S S Iyer; E T Moser; C Singer; K D Sethi
Journal:  J Neurol Neurosurg Psychiatry       Date:  2006-01       Impact factor: 10.154

7.  Efficacy and safety of incobotulinumtoxinA (NT 201, XEOMIN®, botulinum neurotoxin type A, without accessory proteins) in patients with cervical dystonia.

Authors:  Cynthia L Comella; Joseph Jankovic; Daniel D Truong; Angelika Hanschmann; Susanne Grafe
Journal:  J Neurol Sci       Date:  2011-07-18       Impact factor: 3.181

8.  Efficacy and safety of botulinum type A toxin (Dysport) in cervical dystonia: results of the first US randomized, double-blind, placebo-controlled study.

Authors:  Daniel Truong; Drake D Duane; Joseph Jankovic; Carlos Singer; Lauren C Seeberger; Cynthia L Comella; Mark F Lew; Robert L Rodnitzky; Fabio O Danisi; James P Sutton; P David Charles; Robert A Hauser; Geoffrey L Sheean
Journal:  Mov Disord       Date:  2005-07       Impact factor: 10.338

9.  Botulinum toxin and pregnancy.

Authors:  Erica de Oliveira Monteiro
Journal:  Skinmed       Date:  2006 Nov-Dec

10.  Treatment of severe achalasia during pregnancy with esophagoscopic injection of botulinum toxin A: a case report.

Authors:  T Wataganara; S Leelakusolvong; P Sunsaneevithayakul; C Vantanasiri
Journal:  J Perinatol       Date:  2009-09       Impact factor: 2.521
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