Literature DB >> 30363728

Pharmacological inhibition of aberrant transcription factor complexes in inversion 16 acute myeloid leukemia.

Sandeep Potluri1, Daniel Coleman1, Constanze Bonifer1.   

Abstract

Entities:  

Year:  2018        PMID: 30363728      PMCID: PMC6182015          DOI: 10.21037/sci.2018.09.03

Source DB:  PubMed          Journal:  Stem Cell Investig        ISSN: 2306-9759


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  27 in total

1.  CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.

Authors:  John Anto Pulikkan; Mahesh Hegde; Hafiz Mohd Ahmad; Houda Belaghzal; Anuradha Illendula; Jun Yu; Kelsey O'Hagan; Jianhong Ou; Carsten Muller-Tidow; Scot A Wolfe; Lihua Julie Zhu; Job Dekker; John Hackett Bushweller; Lucio Hernán Castilla
Journal:  Cell       Date:  2018-06-28       Impact factor: 41.582

2.  Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis.

Authors:  Anindya Chatterjee; Joydeep Ghosh; Baskar Ramdas; Raghuveer Singh Mali; Holly Martin; Michihiro Kobayashi; Sasidhar Vemula; Victor H Canela; Emily R Waskow; Valeria Visconte; Ramon V Tiu; Catherine C Smith; Neil Shah; Kevin D Bunting; H Scott Boswell; Yan Liu; Rebecca J Chan; Reuben Kapur
Journal:  Cell Rep       Date:  2014-11-13       Impact factor: 9.423

3.  DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation.

Authors:  Georg E Winter; Dennis L Buckley; Joshiawa Paulk; Justin M Roberts; Amanda Souza; Sirano Dhe-Paganon; James E Bradner
Journal:  Science       Date:  2015-05-21       Impact factor: 47.728

Review 4.  BET inhibitors: a novel epigenetic approach.

Authors:  D B Doroshow; J P Eder; P M LoRusso
Journal:  Ann Oncol       Date:  2017-08-01       Impact factor: 32.976

5.  Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.

Authors:  Anuradha Illendula; John A Pulikkan; Hongliang Zong; Jolanta Grembecka; Liting Xue; Siddhartha Sen; Yunpeng Zhou; Adam Boulton; Aravinda Kuntimaddi; Yan Gao; Roger A Rajewski; Monica L Guzman; Lucio H Castilla; John H Bushweller
Journal:  Science       Date:  2015-02-13       Impact factor: 47.728

6.  Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice.

Authors:  R K Hyde; L Zhao; L Alemu; P P Liu
Journal:  Leukemia       Date:  2015-03-06       Impact factor: 11.528

7.  RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML.

Authors:  Justin Loke; Salam A Assi; Maria Rosaria Imperato; Anetta Ptasinska; Pierre Cauchy; Yura Grabovska; Natalia Martinez Soria; Manoj Raghavan; H Ruud Delwel; Peter N Cockerill; Olaf Heidenreich; Constanze Bonifer
Journal:  Cell Rep       Date:  2017-05-23       Impact factor: 9.423

8.  Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers.

Authors:  Anuradha Illendula; Jane Gilmour; Jolanta Grembecka; Venkata Sesha Srimath Tirumala; Adam Boulton; Aravinda Kuntimaddi; Charles Schmidt; Lixin Wang; John A Pulikkan; Hongliang Zong; Mahmut Parlak; Cem Kuscu; Anna Pickin; Yunpeng Zhou; Yan Gao; Lauren Mishra; Mazhar Adli; Lucio H Castilla; Roger A Rajewski; Kevin A Janes; Monica L Guzman; Constanze Bonifer; John H Bushweller
Journal:  EBioMedicine       Date:  2016-04-29       Impact factor: 8.143

9.  Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause.

Authors:  Roberta Scognamiglio; Nina Cabezas-Wallscheid; Marc Christian Thier; Sandro Altamura; Alejandro Reyes; Áine M Prendergast; Daniel Baumgärtner; Larissa S Carnevalli; Ann Atzberger; Simon Haas; Lisa von Paleske; Thorsten Boroviak; Philipp Wörsdörfer; Marieke A G Essers; Ulrich Kloz; Robert N Eisenman; Frank Edenhofer; Paul Bertone; Wolfgang Huber; Franciscus van der Hoeven; Austin Smith; Andreas Trumpp
Journal:  Cell       Date:  2016-02-11       Impact factor: 41.582

10.  Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

Authors:  Anetta Ptasinska; Salam A Assi; Natalia Martinez-Soria; Maria Rosaria Imperato; Jason Piper; Pierre Cauchy; Anna Pickin; Sally R James; Maarten Hoogenkamp; Dan Williamson; Mengchu Wu; Daniel G Tenen; Sascha Ott; David R Westhead; Peter N Cockerill; Olaf Heidenreich; Constanze Bonifer
Journal:  Cell Rep       Date:  2014-09-18       Impact factor: 9.423

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  1 in total

1.  Development of a highly sensitive method for detection of FLT3D835Y.

Authors:  Yao Guo; Honghua Sun; Dengyang Zhang; Yuming Zhao; Mingxia Shi; Ming Yang; Shu Xing; Xueqi Fu; Ting Bin; Bo Lu; Shunjie Wu; Xiaojun Xu; Xuesong Xu; Yun Chen; Zhizhuang Joe Zhao
Journal:  Biomark Res       Date:  2020-08-12
  1 in total

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