Organosilica Nanoparticles and Medical Imaging.

Medical imaging technology using nanoparticles has several advantages from it varies functional properties. As we described previous chapters, mesoporous silica nanoparticles demonstrated great contribution for nanomedicine progress and it has been expected to cause an innovation in medical field. Recently we developed a novel type of silica nanoparticles, organosilica nanoparticles. Organosilica nanoparticles are both structurally and functionally different from common silica nanoparticles by including mesoporous silica nanoparticles. The organosilica nanoparticles are inherent organic-inorganic hybrid nanomaterials. The interior and exterior functionalities of organosilica nanoparticles are effective for their internal and surface functionalization. Medical imaging using organosilica nanoparticles is making a new field of nano-medical imaging. Multifunctionalizations peculiar to organosilica nanoparticles enable to construct novel medical imaging system. In this chapter we will introduce organosilica nanoparticles, and its applications on advanced medical imaging.