Zeina Akiki1,2,3, Souheil Hallit1,4, Nelly Layoun5, Michelle Cherfane6, Hala Sacre1,7, Mirna Waked8, Pascale Salameh1,5,9. 1. Epidemiologie Clinique et Toxicologie, INSPECT-LB: Institut National de Sante Publique , Epidemiologie Clinique et Toxicologie, Beirut , Lebanon. 2. Faculty of Nursing and Health Sciences, Notre Dame Louaize University , Barsa , Lebanon. 3. Faculty of Public Health, Sainte Famille University , Batroun , Lebanon. 4. Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK) , Jounieh , Lebanon. 5. School of Pharmacy, Lebanese International University , Beirut , Lebanon. 6. Drug Information Center, Order of Pharmacists in Lebanon , Beirut , Lebanon. 7. Faculty of Medicine, Balamand University, Balamand , Lebanon. 8. Faculty of Pharmacy, Lebanese University , Beirut , Lebanon. 9. Faculty of Medicine, Lebanese University , Beirut , Lebanon.
Abstract
Objective: We aimed to validate the Arabic version of the St George's Respiratory Questionnaire (SGRQ) for use in Lebanese Chronic obstructive pulmonary disease (COPD) and asthma patients and to identify risk factors that might affect the quality of life in these patients. Methods: COPD (n = 90) and asthma patients (n = 124) were recruited from the outpatient clinics of the Pulmonology department of a university hospital and a medical center in Beirut. They filled out a standardized questionnaire. The total SGRQ score and the component scores (symptoms, activity and impacts) were calculated. To confirm the SGRQ validity in the Lebanese population, factor analyses were applied for the whole sample, only asthma and only COPD patients, respectively. The associations between the total SGRQ score and FEV1% predicted, CCQ score and MRC scale were assessed. Multiple linear regression models were used to evaluate the association between the total SGRQ scores and the socio-demographics and the diseases risk factors. Results: COPD patients had a higher SGRQ total and subscales scores compared to asthma patients. A high Cronbach's alpha was found for the whole sample (0.802), only COPD patients (0.833) and only asthma patients (0.734). A significant negative correlation was found between FEV1% predicted and the total SGRQ scores. Occupational exposure, BMI and previous waterpipe smoking were among the factors that significantly and positively influenced a higher SGRQ score. Conclusions: The Lebanese version of the SGRQ emerges as a good health-related quality of life evaluative instrument that is reasonable to be used in COPD and asthma patients in Lebanon.
Objective: We aimed to validate the Arabic version of the St George's Respiratory Questionnaire (SGRQ) for use in Lebanese Chronic obstructive pulmonary disease (COPD) and asthmapatients and to identify risk factors that might affect the quality of life in these patients. Methods:COPD (n = 90) and asthmapatients (n = 124) were recruited from the outpatient clinics of the Pulmonology department of a university hospital and a medical center in Beirut. They filled out a standardized questionnaire. The total SGRQ score and the component scores (symptoms, activity and impacts) were calculated. To confirm the SGRQ validity in the Lebanese population, factor analyses were applied for the whole sample, only asthma and only COPDpatients, respectively. The associations between the total SGRQ score and FEV1% predicted, CCQ score and MRC scale were assessed. Multiple linear regression models were used to evaluate the association between the total SGRQ scores and the socio-demographics and the diseases risk factors. Results:COPDpatients had a higher SGRQ total and subscales scores compared to asthmapatients. A high Cronbach's alpha was found for the whole sample (0.802), only COPDpatients (0.833) and only asthmapatients (0.734). A significant negative correlation was found between FEV1% predicted and the total SGRQ scores. Occupational exposure, BMI and previous waterpipe smoking were among the factors that significantly and positively influenced a higher SGRQ score. Conclusions: The Lebanese version of the SGRQ emerges as a good health-related quality of life evaluative instrument that is reasonable to be used in COPD and asthmapatients in Lebanon.