Literature DB >> 3035815

Varicella-zoster virus infection of human mononuclear cells.

D H Gilden, A R Hayward, J Krupp, M Hunter-Laszlo, J C Huff, A Vafai.   

Abstract

Varicella-zoster virus (VZV) DNA was detected in mononuclear cells (MNC) of 7 humans with acute zoster 1-23 days after the onset of skin lesions. To further study the interaction of VZV with human MNC, cells obtained from seropositive normal donors were infected with VZV and analyzed for the presence of viral DNA and proteins. VZV-DNA was detected in T, B, and OKM 1 (monocyte-macrophage) positive cells, and virus-specific proteins were demonstrated by indirect immunofluorescence and immunoprecipitation. Hybridization studies revealed that VZV-DNA did not replicate in human MNC.

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Year:  1987        PMID： 3035815     DOI： 10.1016/0168-1702(87)90074-8

Source DB:  PubMed          Journal:  Virus Res        ISSN： 0168-1702            Impact factor:   3.303


  16 in total

1.  Non-productive infection of human newborn blood mononuclear cells with herpes simplex virus: effect on T cell activation, IL-2 production and proliferation.

Authors:  A Hayward; M Laszlo; M Turman; A Vafai; D Tedder
Journal:  Clin Exp Immunol       Date:  1988-11       Impact factor: 4.330

2.  Tropism of varicella-zoster virus for human tonsillar CD4(+) T lymphocytes that express activation, memory, and skin homing markers.

Authors:  Chia-Chi Ku; Jorge A Padilla; Charles Grose; Eugene C Butcher; Ann M Arvin
Journal:  J Virol       Date:  2002-11       Impact factor: 5.103

3.  Simian varicella virus pathogenesis.

Authors:  Ravi Mahalingam; Ilhem Messaoudi; Don Gilden
Journal:  Curr Top Microbiol Immunol       Date:  2010       Impact factor: 4.291

Review 4.  Herpes simplex virus-1 and varicella-zoster virus latency in ganglia.

Authors:  Bradley M Mitchell; David C Bloom; Randall J Cohrs; Donald H Gilden; Peter G E Kennedy
Journal:  J Neurovirol       Date:  2003-04       Impact factor: 2.643

5.  Persistence of varicella zoster virus DNA in saliva after herpes zoster.

Authors:  Maria A Nagel; Alexander Choe; Randall J Cohrs; Igor Traktinskiy; Kyle Sorensen; Satish K Mehta; Duane L Pierson; Stephen K Tyring; Kassie Haitz; Catherine Digiorgio; Whitney Lapolla; Don Gilden
Journal:  J Infect Dis       Date:  2011-09-15       Impact factor: 5.226

6.  Persistence of varicella-zoster virus DNA in blood mononuclear cells of patients with varicella or zoster.

Authors:  D H Gilden; M Devlin; M Wellish; R Mahalingham; C Huff; A Hayward; A Vafai
Journal:  Virus Genes       Date:  1989-08       Impact factor: 2.332

7.  Varicella-zoster virus (VZV) transcription during latency in human ganglia: construction of a cDNA library from latently infected human trigeminal ganglia and detection of a VZV transcript.

Authors:  R J Cohrs; K Srock; M B Barbour; G Owens; R Mahalingam; M E Devlin; M Wellish; D H Gilden
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

8.  Chronic varicella-zoster virus ganglionitis--a possible cause of postherpetic neuralgia.

Authors:  Donald H Gilden; Randall J Cohrs; Anthony R Hayward; Mary Wellish; Ravi Mahalingam
Journal:  J Neurovirol       Date:  2003-06       Impact factor: 2.643

9.  Regulation of varicella-zoster virus gene expression in human T lymphocytes.

Authors:  L P Perera; J D Mosca; W T Ruyechan; J Hay
Journal:  J Virol       Date:  1992-09       Impact factor: 5.103

10.  Downregulation of class I major histocompatibility complex surface expression by varicella-zoster virus involves open reading frame 66 protein kinase-dependent and -independent mechanisms.

Authors:  Amie J Eisfeld; Michael B Yee; Angela Erazo; Allison Abendroth; Paul R Kinchington
Journal:  J Virol       Date:  2007-06-13       Impact factor: 5.103
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