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Literature DB >> 30357553

Small leucine rich proteoglycans in host immunity and renal diseases.

Wei Zou¹, Junhui Wan², Min Li², Juanjuan Xing³, Qi Chen², Zhi Zhang², Yi Gong².

Abstract

The small leucine rich proteoglycans (SLRPs), structurally consisting of protein cores and various glycosaminoglycan side chains, are grouped into five classes based on common structural and functional properties. Besides being an important structural component of extracellular matrix (ECM), SLRPs have been implicated in the complex network of signal transduction and host immune responses. The focus of this review is on SLRPs in host immunity. Because host immunity plays an important part in the pathogenesis of renal diseases, the role of SLRPs in this set of diseases will also be discussed.

Entities: Chemical

Keywords: Host immunity; Renal diseases; SLRPs; TLR 2/4

Year: 2018 PMID： 30357553 PMCID： PMC6946788 DOI： 10.1007/s12079-018-0489-8

Source DB: PubMed Journal: J Cell Commun Signal ISSN： 1873-9601 Impact factor: 5.908

83 in total

1. Effect of adenovirus-mediated overexpression of decorin on metalloproteinases, tissue inhibitors of metalloproteinases and cytokines secretion by human gingival fibroblasts.

Authors: Ayman Al Haj Zen; Antoine Lafont; Eric Durand; Camille Brasselet; Patricia Lemarchand; Gaston Godeau; Bruno Gogly
Journal: Matrix Biol Date: 2003-05 Impact factor: 11.583

2. FGF-2- and TGF-β1-induced downregulation of lumican and keratocan in activated corneal keratocytes by JNK signaling pathway.

Authors: Jian Chen; Julie Wong-Chong; Nirmala SundarRaj
Journal: Invest Ophthalmol Vis Sci Date: 2011-11-21 Impact factor: 4.799

Review 3. Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis.

Authors: Hans-Joachim Anders; Liliana Schaefer
Journal: J Am Soc Nephrol Date: 2014-04-24 Impact factor: 10.121

4. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.

Authors: Andrea Babelova; Kristin Moreth; Wasiliki Tsalastra-Greul; Jinyang Zeng-Brouwers; Oliver Eickelberg; Marian F Young; Peter Bruckner; Josef Pfeilschifter; Roland M Schaefer; Hermann-Josef Gröne; Liliana Schaefer
Journal: J Biol Chem Date: 2009-07-15 Impact factor: 5.157

5. Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease.

Authors: W A Border; N A Noble; T Yamamoto; J R Harper; Y u Yamaguchi; M D Pierschbacher; E Ruoslahti
Journal: Nature Date: 1992-11-26 Impact factor: 49.962

6. Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1.

Authors: Eric C Carlson; Michelle Lin; Chia-Yang Liu; Winston W-Y Kao; Victor L Perez; Eric Pearlman
Journal: J Biol Chem Date: 2007-10-02 Impact factor: 5.157

7. Decorin transfection in human mesangial cells downregulates genes playing a role in the progression of fibrosis.

Authors: Antonia Costacurta; Giovanna Priante; Angela D'Angelo; Luigi Chieco-Bianchi; Salvatore Cantaro
Journal: J Clin Lab Anal Date: 2002 Impact factor: 2.352

Review 8. Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease.

Authors: Geir Christensen; Kate M Herum; Ida G Lunde
Journal: Matrix Biol Date: 2018-01-12 Impact factor: 11.583

9. Transcriptome analysis of endothelial cell gene expression induced by growth on matrigel matrices: identification and characterization of MAGP-2 and lumican as novel regulators of angiogenesis.

Authors: Allan R Albig; Thessa G Roy; Darryl J Becenti; William P Schiemann
Journal: Angiogenesis Date: 2007-07-14 Impact factor: 9.596

Small leucine rich proteoglycans in host immunity and renal diseases.

1. Effect of adenovirus-mediated overexpression of decorin on metalloproteinases, tissue inhibitors of metalloproteinases and cytokines secretion by human gingival fibroblasts.

2. FGF-2- and TGF-β1-induced downregulation of lumican and keratocan in activated corneal keratocytes by JNK signaling pathway.

Review 3. Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis.

4. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.

5. Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease.

6. Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1.

7. Decorin transfection in human mesangial cells downregulates genes playing a role in the progression of fibrosis.

Review 8. Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease.

9. Transcriptome analysis of endothelial cell gene expression induced by growth on matrigel matrices: identification and characterization of MAGP-2 and lumican as novel regulators of angiogenesis.

10. Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy.

Review 1. Proteoglycans in Toll-like receptor responses and innate immunity.

2. Osteomodulin positively regulates osteogenesis through interaction with BMP2.

3. Biglycan Is a Novel Mineralocorticoid Receptor Target Involved in Aldosterone/Salt-Induced Glomerular Injury.

Review 4. DAMPs in Unilateral Ureteral Obstruction.