Paweł Marczuk1,2, Michał J Kubisa1,2,3, Michał Święch1,2, Maciej Walędziak1, Piotr Kowalewski1, Piotr Major4,5, Michał Pędziwiatr4,5, Krzysztof Paśnik1, Michał R Janik6. 1. Department of General, Oncologic, Metabolic and Thoracic Surgery, Military Institute of Medicine, Ul. Szaserów 128, 04-141, Warsaw, Poland. 2. Medical University in Warsaw, Warsaw, Poland. 3. Department of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology (CEPT), Warsaw, Poland. 4. 2nd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland. 5. Centre for Research, Training and Innovation in Surgery (CERTAIN Surgery), Krakow, Poland. 6. Department of General, Oncologic, Metabolic and Thoracic Surgery, Military Institute of Medicine, Ul. Szaserów 128, 04-141, Warsaw, Poland. janiken@gmail.com.
Abstract
INTRODUCTION: As the population ages, there is more interest in bariatric surgery for older patients. There are controversies regarding the safety and effectiveness of surgical weight loss in this population. AIM: The aim of this study was to compare the safety and efficacy of Roux-en-Y gastric bypass in patients over the age of 60 years with younger patients. METHODS: The available literature was searched for eligible studies up to February 2018. Inclusion criteria were reports on mortality, morbidity, percentage excess weight loss (%EWL), remission of diabetes, remission of hypertension, and remission of obstructive sleep apnea. Random effects meta-analyses were performed. RESULTS: The initial search yielded 2000 references. The final meta-analysis involved nine studies and revealed significant differences in mortality (odds ratio 4.38, 95% confidence interval [1.25, 15.31], p = 0.02), morbidity (OR 1.88, CI [1.07, 3.30], p = 0.03), %EWL (mean difference - 5.86, 95% CI [- 9.15, - 2.56], p < 0.001), and remission of comorbidities. CONCLUSION: Higher mortality and morbidity were found in the group of older patients. The analysis suggested lower effectiveness of Roux-en-Y gastric bypass for weight loss and improvement in comorbidity in older patients when compared with younger patients.
INTRODUCTION: As the population ages, there is more interest in bariatric surgery for older patients. There are controversies regarding the safety and effectiveness of surgical weight loss in this population. AIM: The aim of this study was to compare the safety and efficacy of Roux-en-Y gastric bypass in patients over the age of 60 years with younger patients. METHODS: The available literature was searched for eligible studies up to February 2018. Inclusion criteria were reports on mortality, morbidity, percentage excess weight loss (%EWL), remission of diabetes, remission of hypertension, and remission of obstructive sleep apnea. Random effects meta-analyses were performed. RESULTS: The initial search yielded 2000 references. The final meta-analysis involved nine studies and revealed significant differences in mortality (odds ratio 4.38, 95% confidence interval [1.25, 15.31], p = 0.02), morbidity (OR 1.88, CI [1.07, 3.30], p = 0.03), %EWL (mean difference - 5.86, 95% CI [- 9.15, - 2.56], p < 0.001), and remission of comorbidities. CONCLUSION: Higher mortality and morbidity were found in the group of older patients. The analysis suggested lower effectiveness of Roux-en-Y gastric bypass for weight loss and improvement in comorbidity in older patients when compared with younger patients.
Authors: Ivy N Haskins; Tammy Ju; Ashlyn E Whitlock; Lisbi Rivas; Richard L Amdur; Paul P Lin; Khashayar Vaziri Journal: Obes Surg Date: 2018-09 Impact factor: 4.129
Authors: Stephanie E Dunkle-Blatter; Michael R St Jean; Carly Whitehead; William Strodel; Peter N Bennotti; Christopher Still; Mary Jane Reed; Craig G Wood; Anthony T Petrick Journal: Surg Obes Relat Dis Date: 2007-02-27 Impact factor: 4.734
Authors: Y Van Nieuwenhove; E Spriet; T Sablon; E Van Daele; W Willaert; W Ceelen; P Pattyn Journal: Acta Chir Belg Date: 2016-06-02 Impact factor: 1.090
Authors: Piotr Małczak; Magdalena Pisarska; Major Piotr; Michał Wysocki; Andrzej Budzyński; Michał Pędziwiatr Journal: Obes Surg Date: 2017-01 Impact factor: 4.129
Authors: Antonio J Martínez-Ortega; Gabriel Olveira; José L Pereira-Cunill; Carmen Arraiza-Irigoyen; José M García-Almeida; José A Irles Rocamora; María J Molina-Puerta; Juan B Molina Soria; Juana M Rabat-Restrepo; María I Rebollo-Pérez; María P Serrano-Aguayo; Carmen Tenorio-Jiménez; Francisco J Vílches-López; Pedro P García-Luna Journal: Nutrients Date: 2020-07-06 Impact factor: 5.717
Authors: Rishi Singhal; Islam Omar; Brijesh Madhok; Yashasvi Rajeev; Yitka Graham; Abd A Tahrani; Christian Ludwig; Tom Wiggins; Kamal Mahawar Journal: Obes Surg Date: 2022-05-05 Impact factor: 3.479
Authors: Grace F Chao; Karan R Chhabra; Jie Yang; Jyothi R Thumma; David E Arterburn; Andrew M Ryan; Dana A Telem; Justin B Dimick Journal: Ann Surg Date: 2020-11-17 Impact factor: 13.787