MOF-Derived Porous Ni2P/Graphene Composites with Enhanced Electrochemical Properties for Sensitive Nonenzymatic Glucose Sensing.

Herein, we report a high-performance electrocatalyst by orientationally growing Ni2P nanoparticles in situ on graphene film (Ni2P/G) for nonenzymatic glucose sensors in alkaline media. The combination of highly active Ni2P and stable graphene film with rapid conductivity enables this composite to display excellent electrochemical activity toward glucose with enhanced electron transfer rate and steadiness. With Ni-MOF-74 as a precursor, Ni2P/G showed even metal distribution, massive exposure of active sites, and spatially ordered structure. Benefiting from the synergistic reaction of Ni2P particles and graphene, this metal-organic frameworks (MOF)-derived composite exhibited high electrocatalytic activity and specificity toward glucose electrooxidation. Under optimized conditions, a wide linear response was obtained from 5 μM to 1.4 mM with a detection limit of 0.44 μM. Furthermore, an excellent linear response ( R2 = 0.9897) was also obtained by a Ni2P/G modified electrode in human serum with the concentration of glucose ranging from 1 to 8 mM, indicating that the Ni2P/G platform could be utilized for glucose monitoring in practical life.