| Literature DB >> 3035043 |
F Galdiero, M A Tufano, F Rossi, W Filippelli, D De Santis, C Matera, L Berrino, E Marmo.
Abstract
The cardiovascular effects of porins were evaluated using porins isolated from Salmonella typhimurium SH5014. In dogs porins depress arterial systemic pressure, vasomotor reactivity of norepinephrine and peripheral vagal stimulation. They are capable of modifying the sinocarotidal baroreceptor reactivity. In mice porins increase the cardiotoxic effects of isoprenaline, thyroxine, emetine and of p-nitrophenol. In rats porins increase the arrhythmogenic and lethal effects of BaCl2 and also give rise to renal lesions, probably at the tubular level.Entities:
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Year: 1986 PMID： 3035043
Source DB: PubMed Journal: J Med ISSN： 0025-7850