Yasutake Tomata1, Shu Zhang1, Yumi Sugawara1, Ichiro Tsuji1. 1. Division of Epidemiology, Department of Health Informatics and Public Health, Graduate School of Medicine, Tohoku University School of Public Health, Sendai, Japan.
Abstract
OBJECTIVES: This study examined the hypothesis that time spent walking daily has a marked impact on incident dementia. METHODS/ DESIGN: First, we analyzed data from a Japanese cohort (n = 13 990 aged ≥65 y) to obtain hazard ratios. Time spent walking per day (<0.5, 0.5-1, or ≥1 h) was assessed using a self-reported questionnaire. Data on 5.7-year incident dementia were retrieved from the public long-term care insurance database. After estimating the multivariate-adjusted hazard ratios (HRs) of incident dementia using the Cox model, the population attributable fraction (PAF) was calculated using the prevalence in a representative Japanese survey, the "National Health and Nutrition Survey". RESULTS: The time spent walking per day showed an inverse association with incident dementia: the multiple-adjusted HRs (95% confidence intervals) were 1.00 (reference) for less than 0.5 hour, 0.81 [0.71, 0.92] for 0.5 to 1 hour, and 0.72 [0.62, 0.84] for more than or equal to 1 hour. Our estimates indicate that 18.1% of dementia cases would be attributable to walking if all subjects walked more than or equal to 1 h/d and 14.0% if subjects increased their daily time spent walking to one level above the present one (<0.5 to 0.5-1 or 0.5-1 to ≥1 h). CONCLUSIONS: Our results suggest that the daily time spent walking has a considerable preventive impact on incident dementia in Japan.
OBJECTIVES: This study examined the hypothesis that time spent walking daily has a marked impact on incident dementia. METHODS/ DESIGN: First, we analyzed data from a Japanese cohort (n = 13 990 aged ≥65 y) to obtain hazard ratios. Time spent walking per day (<0.5, 0.5-1, or ≥1 h) was assessed using a self-reported questionnaire. Data on 5.7-year incident dementia were retrieved from the public long-term care insurance database. After estimating the multivariate-adjusted hazard ratios (HRs) of incident dementia using the Cox model, the population attributable fraction (PAF) was calculated using the prevalence in a representative Japanese survey, the "National Health and Nutrition Survey". RESULTS: The time spent walking per day showed an inverse association with incident dementia: the multiple-adjusted HRs (95% confidence intervals) were 1.00 (reference) for less than 0.5 hour, 0.81 [0.71, 0.92] for 0.5 to 1 hour, and 0.72 [0.62, 0.84] for more than or equal to 1 hour. Our estimates indicate that 18.1% of dementia cases would be attributable to walking if all subjects walked more than or equal to 1 h/d and 14.0% if subjects increased their daily time spent walking to one level above the present one (<0.5 to 0.5-1 or 0.5-1 to ≥1 h). CONCLUSIONS: Our results suggest that the daily time spent walking has a considerable preventive impact on incident dementia in Japan.