| Literature DB >> 30349607 |
Aneta L Zygulska1, Krzysztof Krzemieniecki2, Anna Sowa-Staszczak2.
Abstract
There are not effective therapies for metastatic unresectable, non-RAI-avid thyroid carcinomas. Fortunately, thyroid carcinomas represent a promising paradigm for targeted therapy due to the presence of activing mutations of genes coding the kinase tyrosines which are involved in all functions of cancer cells (such as: growth or invasion). In this paper an efficacy and toxicity of sorafenib, one of the multi-kinase inhibitors in thyroid carcinomas treatment is presented.Entities:
Keywords: multi-kinase inhibitor; sorafenib; thyroid carcinoma
Year: 2013 PMID: 30349607 PMCID: PMC6193511 DOI: 10.17925/EE.2013.09.01.28
Source DB: PubMed Journal: Eur Endocrinol ISSN: 1758-3772