Literature DB >> 3034788

Flow cytometry derived DNA content of the primary lesions of advanced germ cell tumours.

G W Sledge, J N Eble, B J Roth, B P Wuhrman, L H Einhorn.   

Abstract

We currently lack good prognostic indicators for patients with advanced disseminated germ cell tumours (GCT). An analysis of archival tumour samples of forty-nine patients with advanced GCT for flow cytometry derived DNA content suggests an inverse relationship between tumour proliferative activity and patient survival. The great majority of patients with advanced GCT have aneuploid tumour subpopulations. This analysis suggests that the survival of patients with advanced GCT may depend in part on kinetic variables present in the primary tumour.

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Year:  1987        PMID: 3034788     DOI: 10.1111/j.1365-2605.1987.tb00172.x

Source DB:  PubMed          Journal:  Int J Androl        ISSN: 0105-6263


  2 in total

1.  Automated image analysis DNA cytometry in testicular cancer.

Authors:  R A Bürger; U Witzsch; H Engel; D Potratz; M Stöckle
Journal:  Urol Res       Date:  1994

2.  DNA ploidy in primary testicular cancer.

Authors:  S D Fosså; J M Nesland; E O Pettersen; O Amellem; H Waehre; K Heimdal
Journal:  Br J Cancer       Date:  1991-11       Impact factor: 7.640

  2 in total

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