| Literature DB >> 3034768 |
M Ito, E Ishida, F Tanabe, S Shigeta, Y Watanabe, Y Kawade.
Abstract
Murine peritoneal macrophages pretreated with interferon (IFN)-alpha and then stimulated by opsonized zymosan produced two to three times more LTB4 than untreated macrophages. However, PGE2 production was not changed by IFN-alpha. Meanwhile, IFN-gamma did not affect the production of LTB4 and PGE2. From the results it is considered that IFN-alpha can modulate inflammation or host defence through the production of LTB4.Entities:
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Year: 1987 PMID： 3034768 PMCID： PMC1453281
Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397