Literature DB >> 3034676

Absorption mode two-dimensional NOE spectroscopy of exchangeable protons in oligonucleotides.

V Sklenár, B R Brooks, G Zon, A Bax.   

Abstract

A new NMR method is described for the generation of absorption mode two-dimensional NOE spectra of oligonucleotides in H2O solution. The method yields spectra that are free of baseline distortions with excellent suppression of the intense H2O resonance. The method is demonstrated for a sample of the dodecamer d(CGCGAATTCGCG)2. All exchangeable base protons are identified and a number of new types of NOE connectivities are observed.

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Year:  1987        PMID: 3034676     DOI: 10.1016/0014-5793(87)80699-3

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  14 in total

1.  Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin.

Authors:  M Mrksich; W S Wade; T J Dwyer; B H Geierstanger; D E Wemmer; P B Dervan
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

2.  RNA unrestrained molecular dynamics ensemble improves agreement with experimental NMR data compared to single static structure: a test case.

Authors:  Robert A Beckman; David Moreland; Shirley Louise-May; Christine Humblet
Journal:  J Comput Aided Mol Des       Date:  2006-09-28       Impact factor: 3.686

3.  Thermodynamic and base-pairing studies of matched and mismatched DNA dodecamer duplexes containing cis-syn, (6-4) and Dewar photoproducts of TT.

Authors:  Y Jing; J F Kao; J S Taylor
Journal:  Nucleic Acids Res       Date:  1998-08-15       Impact factor: 16.971

4.  Study of structure, base-pair opening kinetics and proton exchange mechanism of the d-(AATTGCAATT) self-complementary oligodeoxynucleotide in solution.

Authors:  M Kochoyan; G Lancelot; J L Leroy
Journal:  Nucleic Acids Res       Date:  1988-08-11       Impact factor: 16.971

5.  Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex.

Authors:  D E Gilbert; G A van der Marel; J H van Boom; J Feigon
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Non-contiguous regions of Z-DNA in a DNA dodecamer.

Authors:  N Hua; G A van der Marel; J H van Boom; J Feigon
Journal:  Nucleic Acids Res       Date:  1989-10-11       Impact factor: 16.971

7.  Polypurine/polypyrimidine hairpins form a triple helix structure at low pH.

Authors:  M M Mooren; D E Pulleyblank; S S Wijmenga; M J Blommers; C W Hilbers
Journal:  Nucleic Acids Res       Date:  1990-11-25       Impact factor: 16.971

8.  Structural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopy.

Authors:  X L Yang; H Sugiyama; S Ikeda; I Saito; A H Wang
Journal:  Biophys J       Date:  1998-09       Impact factor: 4.033

9.  Water molecule binding and lifetimes on the DNA duplex d(CGCGAATTCGCG)2.

Authors:  D Zhou; R G Bryant
Journal:  J Biomol NMR       Date:  1996-07       Impact factor: 2.835

10.  The binding modes of a rationally designed photoactivated DNA nuclease determined by NMR.

Authors:  H P Spielmann; P A Fagan; T M Bregant; R D Little; D E Wemmer
Journal:  Nucleic Acids Res       Date:  1995-05-11       Impact factor: 16.971

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