Literature DB >> 3034574

Contactpoint analysis of the HeLa nuclear factor I recognition site reveals symmetrical binding at one side of the DNA helix.

E de Vries, W van Driel, S J van den Heuvel, P C van der Vliet.   

Abstract

Nuclear factor I (NFI) is a HeLa sequence-specific DNA-binding protein that is required for initiation of adenovirus (Ad) DNA replication and may be involved in the expression of several cellular genes. The interaction between NFI and its binding site on the Ad2 origin has been studied. Methylation interference and protection, u.v. irradiation of 5-BrdU substituted DNA and ethylation interference revealed major groove contacts with G and T, and phosphate backbone contacts. Computer stereographics show that the contacts are located in two blocks showing dyad symmetry to each other and 22 out of 23 contacts are accessible from one side of the helix. Inversion of the NFI binding site did not change the NFI dependent stimulation of Ad2 DNA replication in a reconstituted system. All data are compatible with NFI binding as a dimer at one side of the DNA helix.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3034574      PMCID： PMC553372          DOI： 10.1002/j.1460-2075.1987.tb04734.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  45 in total

1.  Purification of nuclear factor I by DNA recognition site affinity chromatography.

Authors:  P J Rosenfeld; T J Kelly
Journal:  J Biol Chem       Date:  1986-01-25       Impact factor: 5.157

2.  In vitro replication directed by a cloned adenovirus origin.

Authors:  G D Pearson; K C Chow; R E Enns; K G Ahern; J L Corden; J A Harpst
Journal:  Gene       Date:  1983-09       Impact factor: 3.688

3.  The N-terminal arms of lambda repressor wrap around the operator DNA.

Authors:  C O Pabo; W Krovatin; A Jeffrey; R T Sauer
Journal:  Nature       Date:  1982-07-29       Impact factor: 49.962

4.  Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7.

Authors:  U Siebenlist; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1980-01       Impact factor: 11.205

5.  Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands.

Authors:  M D Challberg; S V Desiderio; T J Kelly
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

6.  Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma.

Authors:  U Siebenlist; L Hennighausen; J Battey; P Leder
Journal:  Cell       Date:  1984-06       Impact factor: 41.582

7.  Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replication.

Authors:  G J Pruijn; W van Driel; P C van der Vliet
Journal:  Nature       Date:  1986 Aug 14-20       Impact factor: 49.962

8.  Multiple specific contacts between a mammalian transcription factor and its cognate promoters.

Authors:  D Gidoni; W S Dynan; R Tjian
Journal:  Nature       Date:  1984 Nov 29-Dec 5       Impact factor: 49.962

9.  Seventeen base pairs of region I encode a novel tripartite binding signal for SV40 T antigen.

Authors:  K Ryder; E Vakalopoulou; R Mertz; I Mastrangelo; P Hough; P Tegtmeyer; E Fanning
Journal:  Cell       Date:  1985-09       Impact factor: 41.582

10.  Replication of origin containing adenovirus DNA fragments that do not carry the terminal protein.

Authors:  B G van Bergen; P A van der Ley; W van Driel; A D van Mansfeld; P C van der Vliet
Journal:  Nucleic Acids Res       Date:  1983-04-11       Impact factor: 16.971
View more
  69 in total

1.  Transcription of the mouse secretory protease inhibitor p12 gene is activated by the developmentally regulated positive transcription factor Sp1.

Authors:  S Robidoux; P Gosselin; M Harvey; S Leclerc; S L Guérin
Journal:  Mol Cell Biol       Date:  1992-09       Impact factor: 4.272

2.  Transcription factors NFI and NFIII/oct-1 function independently, employing different mechanisms to enhance adenovirus DNA replication.

Authors:  Y M Mul; C P Verrijzer; P C van der Vliet
Journal:  J Virol       Date:  1990-11       Impact factor: 5.103

3.  Transcription factors nuclear factor I and Sp1 interact with the murine collagen alpha 1 (I) promoter.

Authors:  M C Nehls; R A Rippe; L Veloz; D A Brenner
Journal:  Mol Cell Biol       Date:  1991-08       Impact factor: 4.272

4.  Oestrogen facilitates the binding of ubiquitous and liver-enriched nuclear proteins to the apoVLDL II promoter in vivo.

Authors:  J Wijnholds; E Muller; G Ab
Journal:  Nucleic Acids Res       Date:  1991-01-11       Impact factor: 16.971

Review 5.  Recognition mechanisms in the synthesis of animal virus DNA.

Authors:  R T Hay; W C Russell
Journal:  Biochem J       Date:  1989-02-15       Impact factor: 3.857

6.  Two upstream elements activate transcription of a major histocompatibility complex class I gene in vitro.

Authors:  P H Driggers; B A Elenbaas; J B An; I J Lee; K Ozato
Journal:  Nucleic Acids Res       Date:  1992-05-25       Impact factor: 16.971

7.  Binding of a nuclear protein to the rat growth hormone silencer element.

Authors:  R J Roy; P Gosselin; M J Anzivino; D D Moore; S L Guérin
Journal:  Nucleic Acids Res       Date:  1992-02-11       Impact factor: 16.971

8.  Hydroxyl radical footprints reveal novel structural features around the NF I binding site in adenovirus DNA.

Authors:  H Zorbas; L Rogge; M Meisterernst; E L Winnacker
Journal:  Nucleic Acids Res       Date:  1989-10-11       Impact factor: 16.971

9.  Identification of HeLa cell nuclear factors that bind to and activate the early promoter of human polyomavirus BK in vitro.

Authors:  T Chakraborty; G C Das
Journal:  Mol Cell Biol       Date:  1989-09       Impact factor: 4.272

10.  NFI and Oct-1 bend the Ad5 origin in the same direction leading to optimal DNA replication.

Authors:  Monika E Mysiak; Claire Wyman; P Elly Holthuizen; Peter C van der Vliet
Journal:  Nucleic Acids Res       Date:  2004-12-01       Impact factor: 16.971
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.