| Literature DB >> 30345184 |
Baoqiong Liu1, Yan Zhou2, Lingbin Meng1, Holly Skinner3.
Abstract
Limbic encephalitis (LE) is a neurological syndrome that mainly affects mesial temporal lobes. It may present in association with cancer or infection. Limbic encephalitis associated with glutamic acid decarboxylase antibodies (anti-GAD) is rare. Here, we report a case of anti-GAD limbic encephalitis to heighten the awareness of this rare cause of autoimmune encephalitis. Anti-GAD-associated epilepsy is often poorly responsive to seizure medications. Treatment is challenging. Early initiation of immunotherapy is important.Entities:
Keywords: glutamic acid decarboxylase antibodies; immunotherapy; limbic encephalitis; refractory seizures
Year: 2018 PMID: 30345184 PMCID: PMC6181246 DOI: 10.7759/cureus.3125
Source DB: PubMed Journal: Cureus ISSN: 2168-8184