| Literature DB >> 30343725 |
Matthew L Banks1, Margaret E Olson2, Kim D Janda3.
Abstract
The current opioid crisis has reinvigorated interest in the development of therapeutics for opioid use disorder (OUD), and the choice of preclinical translational endpoints is an essential consideration. Antiopioid immunopharmacotherapies (e.g., conjugate vaccines) that sequester drug peripherally, preventing opioids from reaching targeted receptors in the brain, have recently emerged as promising therapeutics.Entities:
Keywords: choice; drug self-administration; hapten; opioid; vaccine
Mesh:
Substances:
Year: 2018 PMID: 30343725 PMCID: PMC6472257 DOI: 10.1016/j.tips.2018.08.001
Source DB: PubMed Journal: Trends Pharmacol Sci ISSN: 0165-6147 Impact factor: 14.819