Literature DB >> 30342234

Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta.

Johanna P Laakkonen1, Johanna Lähteenvuo2, Suvi Jauhiainen2, Tommi Heikura2, Seppo Ylä-Herttuala3.   

Abstract

Vascular endothelial growth factors regulate vascular and lymphatic growth. Dysregulation of VEGF signaling is connected to many pathological states, including hemangiomas, arteriovenous malformations and placental abnormalities. In heart, VEGF gene transfer induces myocardial angiogenesis. Besides vascular and lymphatic endothelial cells, VEGFs affect multiple other cell types. Understanding VEGF biology and its paracrine signaling properties will offer new targets for novel treatments of several diseases.
Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Angiogenesis; Arteriovenous malformation; Heart; Hemangioma; Lymphangiogenesis; Lymphatic vessel; Placenta; VEGF; VEGF receptor; Vascular endothelial growth factor; Vascular tumor

Mesh：

Substances：

Year:  2018        PMID： 30342234     DOI： 10.1016/j.vph.2018.10.005

Source DB:  PubMed          Journal:  Vascul Pharmacol        ISSN： 1537-1891            Impact factor:   5.773


  6 in total

1.  Pressure overload generates a cardiac-specific profile of inflammatory mediators.

Authors:  Matthew O'Brien; Catalin F Baicu; An O Van Laer; Yuhua Zhang; Lindsey T McDonald; Amanda C LaRue; Michael R Zile; Amy D Bradshaw
Journal:  Am J Physiol Heart Circ Physiol       Date:  2020-06-26       Impact factor: 4.733

2.  The Effect of Hypoxia Inducible Factor -1 Alpha and Vascular Endothelial Growth Factor Level in Type 2 Diabetes Microvascular Complications and Development.

Authors:  Rusdiana Rusdiana; Ahmad Moradi; Sry Suryani Widjaja; Mutiara Indah Sari; Hidayat Hidayat; Maya Savira; Rina Amelia; Rusmalawaty Rusmalawaty
Journal:  Med Arch       Date:  2022-04

3.  Comparison of Efficiency and Function of Vascular Endothelial Growth Factor Adenovirus Vectors in Endothelial Cells for Gene Therapy of Placental Insufficiency.

Authors:  Carlo Rossi; Mark Lees; Vedanta Mehta; Tommi Heikura; John Martin; Ian Zachary; Rebecca Spencer; Donald M Peebles; Robert Shaw; Minna Karhinen; Seppo Yla-Herttuala; Anna L David
Journal:  Hum Gene Ther       Date:  2020-11       Impact factor: 5.695

4.  Angiotensin Receptor Blocker and Neprilysin Inhibitor Suppresses Cardiac Dysfunction by Accelerating Myocardial Angiogenesis in Apolipoprotein E-Knockout Mice Fed a High-Fat Diet.

Authors:  Yasunori Suematsu; Kohei Tashiro; Hidetaka Morita; Akihito Ideishi; Takashi Kuwano; Shin-Ichiro Miura
Journal:  J Renin Angiotensin Aldosterone Syst       Date:  2021-08-04       Impact factor: 1.636

Review 5.  Tumor Angiogenesis and Anti-Angiogenic Strategies for Cancer Treatment.

Authors:  Raluca Ioana Teleanu; Cristina Chircov; Alexandru Mihai Grumezescu; Daniel Mihai Teleanu
Journal:  J Clin Med       Date:  2019-12-29       Impact factor: 4.241

6.  Serum vascular endothelial growth factor level is elevated in patients with impaired glucose tolerance and type 2 diabetes mellitus.

Authors:  Xiaomeng Sun; Heng Zhang; Jia Liu; Guang Wang
Journal:  J Int Med Res       Date:  2019-09-23       Impact factor: 1.671
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.