Literature DB >> 30342

Effects of pH on protein binding of lidocaine.

R G Burney, C A DiFazio, J A Foster.   

Abstract

Protein binding of lidocaine (2.5, 5, 10, and 20 microgram/ml in fresh plasma was studied from pH 5.6 to pH 9.8. Percent binding of lidocaine was inversely related to hydrogen-ion and lidocaine concentrations.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 30342     DOI： 10.1213/00000539-197807000-00019

Source DB:  PubMed          Journal:  Anesth Analg        ISSN： 0003-2999            Impact factor:   5.108


  13 in total

Review 1.  [Toxicology of local anesthetics. Clinical, therapeutic and pathological mechanisms].

Authors:  W Zink; B M Graf
Journal:  Anaesthesist       Date:  2003-12       Impact factor: 1.041

2.  Comparison of placental transfer of local anesthetics in perfusates with different pH values in a human cotyledon model.

Authors:  Ryusuke Ueki; Tsuneo Tatara; Nobutaka Kariya; Noriko Shimode; Chikara Tashiro
Journal:  J Anesth       Date:  2009-11-18       Impact factor: 2.078

Review 3.  Clinical features, pathogenesis and management of drug-induced seizures.

Authors:  G Zaccara; G C Muscas; A Messori
Journal:  Drug Saf       Date:  1990 Mar-Apr       Impact factor: 5.606

Review 4.  Clinical pharmacokinetics of local anaesthetics.

Authors:  G T Tucker; L E Mather
Journal:  Clin Pharmacokinet       Date:  1979 Jul-Aug       Impact factor: 6.447

5.  Risk appraisal of narcotic sedation for children.

Authors:  P A Moore; J M Goodson
Journal:  Anesth Prog       Date:  1985 Jul-Aug

Review 6.  Drug kinetics in childbirth.

Authors:  R L Nation
Journal:  Clin Pharmacokinet       Date:  1980 Jul-Aug       Impact factor: 6.447

Review 7.  [Lipid emulsion therapy for local anaesthetic toxicity. (LipidRescue)].

Authors:  K Ott
Journal:  Anaesthesist       Date:  2010-06       Impact factor: 1.041

8.  The clinical relevance of plasma protein binding changes.

Authors:  Jason A Roberts; Federico Pea; Jeffrey Lipman
Journal:  Clin Pharmacokinet       Date:  2013-01       Impact factor: 6.447

9.  Plasma protein binding of etidocaine during pregnancy and labour.

Authors:  D J Morgan; B B Koay; J D Paull
Journal:  Eur J Clin Pharmacol       Date:  1982       Impact factor: 2.953

10.  Pethidine binding in plasma: effects of methodological variables.

Authors:  C La Rosa; L E Mather; D J Morgan
Journal:  Br J Clin Pharmacol       Date:  1984-04       Impact factor: 4.335
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.