Hepatitis E Virus-Associated Acute Encephalitic Parkinsonism.

Hepatitis E virus (HEV) is a common infection worldwide and is an emerging infectious disease in the developed countries. The unique characteristics of HEV is that it displays different epidemiological and clinical characteristics between developing and developed countries. Neurological disorders are emerging extra hepatic manifestations of both acute and chronic Hepatitis E virus infection. We report a 17 year old sportsman presenting with acute encephalitic Parkinsonism concurrent with acute hepatitis. Serology was positive for Hepatitis E virus (HEV) and HEV RNA was confirmed. Patient improved completely with symptomatic treatment. We suggest offering diagnostic testing for Hepatitis E virus in patients of neurological disorders with concurrent liver impairment. © Journal of the Association of Physicians of India 2011.