Literature DB >> 30339876

Rabbit models of human diseases for diagnostics and therapeutics development.

Rose G Mage1, Pedro J Esteves2, Christoph Rader3.   

Abstract

This review presents some examples of studies using the European rabbit (Oryctolagus cuniculus) that have led to, and continue to, contribute to advancement of understanding of human diseases as well as therapeutics development. In addition, we tabulate FDA-approved rabbit polyclonal and rabbit monoclonal antibodies (mAbs) that are used for diagnostic applications, as well as an overview of some "humanized" or otherwise altered rabbit mAbs that are in initial phase I, II, or advanced to phase III clinical trials. Information about endogenous retriviruses learned from studies of rabbits and other members of the order Lagomorpha are summarized as this knowledge now applies to new therapeutics being developed for several human diseases including Multiple Sclerosis, Type 1 Diabetes and Cancer. Published by Elsevier Ltd.

Entities:  

Keywords:  Cancer; Cardiovascular disease; Endogenous retroviruses; Multiple Sclerosis; Ocular diseases; Systemic Lupus Erythematosis

Mesh：

Year:  2018        PMID： 30339876      PMCID： PMC6364550          DOI： 10.1016/j.dci.2018.10.003

Source DB:  PubMed          Journal:  Dev Comp Immunol        ISSN： 0145-305X            Impact factor:   3.636


  49 in total

1.  ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium.

Authors:  A Endo; M Kuroda; Y Tsujita
Journal:  J Antibiot (Tokyo)       Date:  1976-12       Impact factor: 2.649

2.  Establishment and identification of a rabbit model of peritoneal carcinomatosis from gastric cancer.

Authors:  Lie-Jun Mei; Xiao-Jun Yang; Li Tang; Alaa Hammed Al-Shammaa Hassan; Yutaka Yonemura; Yan Li
Journal:  BMC Cancer       Date:  2010-04-01       Impact factor: 4.430

3.  Models of systemic lupus erythematosus: development of autoimmunity following peptide immunizations of noninbred pedigreed rabbits.

Authors:  Geeta Rai; Satyajit Ray; Robyn E Shaw; Paula F Degrange; Rose G Mage; Barbara A Newman
Journal:  J Immunol       Date:  2006-01-01       Impact factor: 5.422

4.  A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus.

Authors:  L A DeGiorgio; K N Konstantinov; S C Lee; J A Hardin; B T Volpe; B Diamond
Journal:  Nat Med       Date:  2001-11       Impact factor: 53.440

Review 5.  B cell and antibody repertoire development in rabbits: the requirement of gut-associated lymphoid tissues.

Authors:  Rose G Mage; Dennis Lanning; Katherine L Knight
Journal:  Dev Comp Immunol       Date:  2006       Impact factor: 3.636

6.  Rabbit endogenous retrovirus-H encodes a functional protease.

Authors:  Cécile Voisset; Richard E Myers; Alex Carne; Paul Kellam; David J Griffiths
Journal:  J Gen Virol       Date:  2003-01       Impact factor: 3.891

7.  Sharing of endogenous lentiviral gene fragments among leporid lineages separated for more than 12 million years.

Authors:  W van der Loo; J Abrantes; P J Esteves
Journal:  J Virol       Date:  2008-12-24       Impact factor: 5.103

8.  Aberrant Epstein-Barr viral infection in systemic lupus erythematosus.

Authors:  Brian D Poole; Amanda K Templeton; Joel M Guthridge; Eric J Brown; John B Harley; Judith A James
Journal:  Autoimmun Rev       Date:  2009-01-22       Impact factor: 9.754

9.  Discovery and analysis of the first endogenous lentivirus.

Authors:  Aris Katzourakis; Michael Tristem; Oliver G Pybus; Robert J Gifford
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-23       Impact factor: 11.205

10.  Identification of a RELIK orthologue in the European hare (Lepus europaeus) reveals a minimum age of 12 million years for the lagomorph lentiviruses.

Authors:  Z Keckesova; L M J Ylinen; G J Towers; R J Gifford; A Katzourakis
Journal:  Virology       Date:  2008-12-13       Impact factor: 3.616
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  5 in total

1.  Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.

Authors:  Rebecca S Goydel; Justus Weber; Haiyong Peng; Junpeng Qi; Jo Soden; Jim Freeth; HaJeung Park; Christoph Rader
Journal:  J Biol Chem       Date:  2020-03-19       Impact factor: 5.157

Review 2.  Hybridoma technology a versatile method for isolation of monoclonal antibodies, its applicability across species, limitations, advancement and future perspectives.

Authors:  Hilal Ahmed Parray; Shivangi Shukla; Sweety Samal; Tripti Shrivastava; Shubbir Ahmed; Chandresh Sharma; Rajesh Kumar
Journal:  Int Immunopharmacol       Date:  2020-05-27       Impact factor: 4.932

3.  Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections.

Authors:  Jessica M Gilbertie; Lauren V Schnabel; Noreen J Hickok; Megan E Jacob; Brian P Conlon; Irving M Shapiro; Javad Parvizi; Thomas P Schaer
Journal:  PLoS One       Date:  2019-08-15       Impact factor: 3.240

4.  Reactivity of selected markers of innate and adaptive immunity in rabbits experimentally infected with antigenic variants of RHD (Lagovirus europaeus/GI.1a).

Authors:  Paulina Niedźwiedzka-Rystwej; Beata Tokarz-Deptuła; Wiesław Deptuła
Journal:  Vet Res Commun       Date:  2021-10-29       Impact factor: 2.816

5.  The rabbit as an animal model to study innate immunity genes: Is it better than mice?

Authors:  João Soares; Ana Pinheiro; Pedro José Esteves
Journal:  Front Immunol       Date:  2022-09-09       Impact factor: 8.786
  5 in total

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