| Literature DB >> 30339861 |
Jiayuan Li1, Gang Ni1, Li Li1, Yanfei Liu1, Zhenpeng Mai1, Renzhong Wang1, Dequan Yu2.
Abstract
Eight new iridal-type triterpenoid derivatives, including two noriridals with ether bridge (1-2); two iridals lactone (3-4), four monocyclic iridals (5-8), together with five known iridals (9-14) were identified from the rhizome of Belamcanda chinensis. Their structures were elucidated on the basis of comprehensive spectroscopic methods and electronic circular dichroism (ECD) calculations. Bioassay results showed that belamcanoxide B (1) exhibited moderated cytotoxic activities against HCT-116 and MCF-7 cell lines with IC50 values of 5.58 and 3.35 μM.Entities:
Keywords: Belamcanda chinensis; Cytotoxic activities; Iridal-type triterpenoids
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Year: 2018 PMID： 30339861 DOI： 10.1016/j.bioorg.2018.08.039
Source DB: PubMed Journal: Bioorg Chem ISSN： 0045-2068 Impact factor: 5.275