Literature DB >> 30339148

Neurotoxic Side Effects Early in the Oxaliplatin Treatment Period in Patients With Colorectal Cancer.

Jenny Drott1, Hans Starkhammar1, Karin Kjellgren1, Carina Berterö1.   

Abstract

PURPOSE: To identify and describe experiences of patients with colorectal cancer (CRC) who have neurotoxic side effects early in the oxaliplatin treatment period, and how neurotoxicity affects their daily lives. PARTICIPANTS &
SETTING: 10 patients with stage II-III CRC were included. All were treated with adjuvant oxaliplatin postoperatively and assessed neurotoxicity via a platform-independent mobile phone-based system. Patients were recruited from two hospitals in southern Sweden from November 2013 to August 2014. METHODOLOGIC APPROACH: Qualitative interview study conducted through open-ended, face-to-face, qualitative interviews. Thematic analysis was used.
FINDINGS: A main theme was identified. IMPLICATIONS FOR NURSING: Nurses have an obligation to communicate the importance of early detection of neurotoxicity. Mobile phone technology seems to be a valuable tool for monitoring patient-reported neurotoxicity to improve communication and supportive care.

Entities:  

Keywords:  chemotherapy; colorectal cancer; daily life; neurotoxicity; qualitative methodology

Mesh:

Substances:

Year:  2018        PMID: 30339148     DOI: 10.1188/18.ONF.690-697

Source DB:  PubMed          Journal:  Oncol Nurs Forum        ISSN: 0190-535X            Impact factor:   2.172


  3 in total

1.  iTRAQ‑based proteomics analysis of the therapeutic effects of combined anticancer bioactive peptides and oxaliplatin on gastric cancer cells.

Authors:  Yanan Xu; Xian Li; Xiulan Su
Journal:  Oncol Rep       Date:  2019-11-11       Impact factor: 3.906

2.  Synergistic antitumor effects of polysaccharides and anthocyanins from Lycium ruthenicum Murr. on human colorectal carcinoma LoVo cells and the molecular mechanism.

Authors:  Xinshu Qin; Xingyu Wang; Ke Xu; Xingbin Yang; Qing Wang; Chao Liu; Xinkun Wang; Xu Guo; Jinyue Sun; Lin Li; Shiqi Li
Journal:  Food Sci Nutr       Date:  2022-04-18       Impact factor: 3.553

3.  Identification of Novel miRNAs, Targeting Genes, Signaling Pathway, and the Small Molecule for Overcoming Oxaliplatin Resistance of Metastatic Colorectal Cancer.

Authors:  Md Misbah; Manoj Kumar; Kuen-Huar Lee; Shing-Chuan Shen
Journal:  Biomed Res Int       Date:  2022-09-19       Impact factor: 3.246

  3 in total

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