Literature DB >> 30338558

Response to ustekinumab in three pediatric patients with alopecia areata.

Abdullah Aleisa1, Yeun Lim2, Samantha Gordon1, Min Ji Her1, Pedro Zancanaro1, Minawaer Abudu1, Sandhya Chowdary Deverapalli1, Abdulaziz Madani1, David Rosmarin1.   

Abstract

Alopecia areata (AA) is relatively common and can have a significant impact on quality of life, especially in a pediatric population. Currently available treatments are often ineffective or have poor safety profiles. Recent studies have highlighted the importance of the Th1 pathway in the pathogenesis of AA, suggesting ustekinumab as a treatment modality for this disease. We present three pediatric AA patients who demonstrated hair regrowth after initiating ustekinumab.
© 2018 Wiley Periodicals, Inc.

Entities:  

Keywords:  alopecia areata; pediatric; treatment; ustekinumab

Mesh:

Substances:

Year:  2018        PMID: 30338558     DOI: 10.1111/pde.13699

Source DB:  PubMed          Journal:  Pediatr Dermatol        ISSN: 0736-8046            Impact factor:   1.588


  10 in total

1.  Immunoendocrinology: When (neuro)endocrinology and immunology meet.

Authors:  Christian A Koch; Alessandro Antonelli
Journal:  Rev Endocr Metab Disord       Date:  2018-12       Impact factor: 6.514

2.  IL-12/IL-23 neutralization is ineffective for alopecia areata in mice and humans.

Authors:  Luana S Ortolan; Sa Rang Kim; Sydney Crotts; Lucy Y Liu; Brittany G Craiglow; Carlos Wambier; Renato S Paschoal; Brett A King; Ali Jabbari
Journal:  J Allergy Clin Immunol       Date:  2019-08-27       Impact factor: 10.793

Review 3.  Alopecia Areata: an Update on Etiopathogenesis, Diagnosis, and Management.

Authors:  Cheng Zhou; Xiangqian Li; Chen Wang; Jianzhong Zhang
Journal:  Clin Rev Allergy Immunol       Date:  2021-08-17       Impact factor: 8.667

Review 4.  The current state of knowledge of the immune ecosystem in alopecia areata.

Authors:  Samuel J Connell; Ali Jabbari
Journal:  Autoimmun Rev       Date:  2022-02-10       Impact factor: 17.390

Review 5.  New and Emerging Therapies for Alopecia Areata.

Authors:  Aunna Pourang; Natasha Atanaskova Mesinkovska
Journal:  Drugs       Date:  2020-05       Impact factor: 9.546

Review 6.  Treatment of pediatric alopecia areata: A systematic review.

Authors:  Virginia R Barton; Atrin Toussi; Smita Awasthi; Maija Kiuru
Journal:  J Am Acad Dermatol       Date:  2021-04-30       Impact factor: 15.487

Review 7.  Learning From Success and Failure: Biologics for Non-approved Skin Diseases.

Authors:  Reinhart Speeckaert; Jo Lambert; Nanja van Geel
Journal:  Front Immunol       Date:  2019-08-08       Impact factor: 7.561

Review 8.  From IL-17 to IFN-γ in inflammatory skin disorders: Is transdifferentiation a potential treatment target?

Authors:  Arno Belpaire; Nanja van Geel; Reinhart Speeckaert
Journal:  Front Immunol       Date:  2022-07-28       Impact factor: 8.786

Review 9.  Alternative uses of ustekinumab for non-indicated dermatological conditions: a systematic review.

Authors:  Sahil Rawal; Sara Kianian; William Guo; Jocellie Marquez; Marissa Ayasse; Katherine A Siamas; Yoojin Lee; Joann Salvemini
Journal:  Arch Dermatol Res       Date:  2021-06-22       Impact factor: 3.017

Review 10.  Alopecia Areata: An Autoimmune Disease of Multiple Players.

Authors:  Poonkiat Suchonwanit; Chaninan Kositkuljorn; Cherrin Pomsoong
Journal:  Immunotargets Ther       Date:  2021-07-29
  10 in total

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