Literature DB >> 30338156

Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance.

Paola Monterroso Diaz1, Samir V Jenkins2, Kinan Alhallak1, Daria Semeniak1, Robert J Griffin2, Ruud P M Dings2, Narasimhan Rajaram1.   

Abstract

There is a critical need to identify patients with radiation-resistant tumors early after treatment commencement. In this study, we use diffuse reflectance spectroscopy (DRS) to investigate changes in vascular oxygenation and total hemoglobin concentration in A549 radiation-sensitive and resistant tumors treated with a clinically relevant dose fraction of 2 Gy. DRS spectra were acquired before, immediately after, 24, and 48 hours after radiation. Our data reveals a significantly higher reoxygenation (sO2) in the radiation-resistant tumors 24 and 48h after treatment, and provides promising evidence that DRS can discern between the reoxygenation trends of radiation-sensitive and resistant tumors.

Entities:  

Year:  2018        PMID： 30338156      PMCID： PMC6191608          DOI： 10.1364/BOE.9.003794

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


  30 in total

1.  Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy.

Authors:  R A Gatenby; H B Kessler; J S Rosenblum; L R Coia; P J Moldofsky; W H Hartz; G J Broder
Journal:  Int J Radiat Oncol Biol Phys       Date:  1988-05       Impact factor: 7.038

2.  Performance of a lookup table-based approach for measuring tissue optical properties with diffuse optical spectroscopy.

Authors:  Brandon S Nichols; Narasimhan Rajaram; James W Tunnell
Journal:  J Biomed Opt       Date:  2012-05       Impact factor: 3.170

3.  Prognostic impact of reoxygenation in advanced cancer of the head and neck during the initial course of chemoradiation or radiotherapy alone.

Authors:  Andreas Dietz; Bernhard Vanselow; Volker Rudat; Christian Conradt; Hagen Weidauer; Friedrich Kallinowski; Ralph Dollner
Journal:  Head Neck       Date:  2003-01       Impact factor: 3.147

4.  Heterogeneity in tumor microvascular response to radiation.

Authors:  M W Dewhirst; R Oliver; C Y Tso; C Gustafson; T Secomb; J F Gross
Journal:  Int J Radiat Oncol Biol Phys       Date:  1990-03       Impact factor: 7.038

5.  Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo.

Authors:  J Quincy Brown; Lee G Wilke; Joseph Geradts; Stephanie A Kennedy; Gregory M Palmer; Nirmala Ramanujam
Journal:  Cancer Res       Date:  2009-03-17       Impact factor: 12.701

6.  Quantitative optical spectroscopy can identify long-term local tumor control in irradiated murine head and neck xenografts.

Authors:  Karthik Vishwanath; Daniel Klein; Kevin Chang; Thies Schroeder; Mark W Dewhirst; Nimmi Ramanujam
Journal:  J Biomed Opt       Date:  2009 Sep-Oct       Impact factor: 3.170

7.  Modulation of the tumor vasculature functionality by ionizing radiation accounts for tumor radiosensitization and promotes gene delivery.

Authors:  Pierre Sonveaux; Chantal Dessy; Agnès Brouet; Bénédicte F Jordan; Vincent Grégoire; Bernard Gallez; Jean-Luc Balligand; Olivier Feron
Journal:  FASEB J       Date:  2002-10-18       Impact factor: 5.191

8.  Xenograft assessment of predictive biomarkers for standard head and neck cancer therapies.

Authors:  Andrew P Stein; Adam D Swick; Molly A Smith; Grace C Blitzer; Robert Z Yang; Sandeep Saha; Paul M Harari; Paul F Lambert; Cheng Z Liu; Randall J Kimple
Journal:  Cancer Med       Date:  2015-01-26       Impact factor: 4.452

9.  Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells.

Authors:  Kinan Alhallak; Samir V Jenkins; David E Lee; Nicholas P Greene; Kyle P Quinn; Robert J Griffin; Ruud P M Dings; Narasimhan Rajaram
Journal:  J Biomed Opt       Date:  2017-06-01       Impact factor: 3.170

10.  A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro.

Authors:  David E Lee; Kinan Alhallak; Samir V Jenkins; Isaac Vargas; Nicholas P Greene; Kyle P Quinn; Robert J Griffin; Ruud P M Dings; Narasimhan Rajaram
Journal:  Sci Rep       Date:  2018-06-11       Impact factor: 4.379
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  6 in total

1.  Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment.

Authors:  Santosh K Paidi; Paola Monterroso Diaz; Sina Dadgar; Samir V Jenkins; Charles M Quick; Robert J Griffin; Ruud P M Dings; Narasimhan Rajaram; Ishan Barman
Journal:  Cancer Res       Date:  2019-02-28       Impact factor: 12.701

2.  Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectroscopy.

Authors:  Joel Rodriguez Troncoso; Paola Monterroso Diaz; David E Lee; Charles M Quick; Narasimhan Rajaram
Journal:  Biomed Opt Express       Date:  2021-06-10       Impact factor: 3.732

3.  Investigation of water bonding status of normal and psoriatic skin in vivo using diffuse reflectance spectroscopy.

Authors:  Chao-Chun Yang; Yun-Yo Yen; Chao-Kai Hsu; Nan-Yu Cheng; Shih-Yu Tzeng; Shih-Jay Chou; Jun-Ming Chang; Sheng-Hao Tseng
Journal:  Sci Rep       Date:  2021-04-26       Impact factor: 4.379

4.  The Potential of Photoacoustic Imaging in Radiation Oncology.

Authors:  Thierry L Lefebvre; Emma Brown; Lina Hacker; Thomas Else; Mariam-Eleni Oraiopoulou; Michal R Tomaszewski; Rajesh Jena; Sarah E Bohndiek
Journal:  Front Oncol       Date:  2022-03-03       Impact factor: 5.738

Review 5.  Optical Imaging Approaches to Investigating Radiation Resistance.

Authors:  Sina Dadgar; Narasimhan Rajaram
Journal:  Front Oncol       Date:  2019-11-05       Impact factor: 6.244

6.  Immunologic Effects of Stereotactic Body Radiotherapy in Dogs with Spontaneous Tumors and the Impact of Intratumoral OX40/TLR Agonist Immunotherapy.

Authors:  Mary-Keara Boss; Remy Watts; Lauren G Harrison; Sophie Hopkins; Lyndah Chow; Erin Trageser; Carina Easton; Susan M LaRue; Daniel Regan; Mark W Dewhirst; Steven Dow
Journal:  Int J Mol Sci       Date:  2022-01-13       Impact factor: 5.923
  6 in total

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