Justyna Swol1, Jan Belohlávek2, Daniel Brodie3, Joseph Bellezzo4, Scott D Weingart5, Zachary Shinar6, Andreas Schober7, Matthew Bachetta8, Jonathan W Haft9, Shingo Ichiba10, Tetsuya Sakamoto11, Giles J Peek12, Roberto Lorusso13, Steven A Conrad14. 1. Department of Pulmonology, Intensive Care Medicine, Paracelsus Medical University, Nuremberg, Germany. Electronic address: jswol@icloud.com. 2. 2nd Department of Medicine, Cardiovascular Medicine, Charles University in Prague U Nemocnice 2, Praha 2, 128 00, Czech Republic. 3. Columbia University College of Physicians and Surgeons/New York-Presbyterian Hospital 630 West 168th Street, New York, NY, 10032, USA. 4. Emergency Room Sharp Memorial Hospital, 7901 Frost St., San Diego, CA, 92123, USA. 5. Department of Emergency Medicine, Division of Emergency Critical Care, Resuscitation and Acute Critical Care Unit, Stony Brook Hospital, 101 Nicolls Road, Stony Brook, NY, 11794-8434, USA. 6. Emergency Room Sharp Memorial Hospital, 7901 Frost St., San Diego, CA 92123, USA. 7. Department of Emergency Medicine Medical, University of Vienna, Währinger Gürtel 18-20/6D, A-1090, Vienna, Austria. 8. Columbia University Medical Center, 161 Fort Washington Ave., Rm 336, New York, NY 10032, USA. 9. Department of Surgery, University of Michigan Health System, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109-5853, USA. 10. Department of Surgical Intensive Care Medicine, Nippon Medical School Hospital, 1-1-5 Sendagi Bunkyo-ku, Tokyo, 113-8603, Japan. 11. Department of Emergency Medicine, Tokyo University School of Medicine, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8606, Japan. 12. Division of Pediatric Cardiothoracic Surgery, Children's Hospital at Montefiore, Bainbridge Avenue, New York, NY, 10467, USA. 13. Cardio-Thoracic Surgery Department, Heart & Vascular Centre, Maastricht University Medical Centre, P. Debyelaan, 25, Maastricht 6202 AZ, the Netherlands. 14. Department of Emergency Medicine, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71103, USA.
Abstract
BACKGROUND: Extracorporeal life support (ECLS) describes the use of blood perfusion devices to provide advanced cardiac or respiratory support. Advances in percutaneous vascular cannula insertion, centrifugal pump technologies, and the miniaturization of extracorporeal devices have simplified ECLS. The intention of this discussion is to review the role of ECLS as a potential rescue method for emergency department (ED) clinicians in critical clinical scenarios and to focus on the prerequisites for managing an ECLS program in an ED setting. DISCUSSION: Possible indications for ECLS cannulation in the ED include ongoing circulatory arrest, shock or refractory hypoxemia and pulmonary embolism with refractory shock. Severe trauma, foreign body obstruction, hypothermia and near drowning are situations in which patients may potentially benefit from ECLS. Early stabilization in the ED can provide a time window for a diagnostic workup and/or urgent procedures, including percutaneous coronary intervention, rewarming or damage control surgery in trauma. The use of ECLS is resource intensive and can be associated with a high risk of complications, especially when performed without previous training. Therefore, ECLS should only be used when the underlying problem is potentially reversible, and the resources are available to address the etiology of organ dysfunction. CONCLUSION: Emergent ECLS has a role in the ED for selected indications in the face of life-threatening conditions. ECLS provides a bridge to recovery, definitive therapy, intervention or surgery. ECLS program requires an appropriately trained staff (physicians, nurses and ECLS specialists), equipment resources and logistical planning.
BACKGROUND: Extracorporeal life support (ECLS) describes the use of blood perfusion devices to provide advanced cardiac or respiratory support. Advances in percutaneous vascular cannula insertion, centrifugal pump technologies, and the miniaturization of extracorporeal devices have simplified ECLS. The intention of this discussion is to review the role of ECLS as a potential rescue method for emergency department (ED) clinicians in critical clinical scenarios and to focus on the prerequisites for managing an ECLS program in an ED setting. DISCUSSION: Possible indications for ECLS cannulation in the ED include ongoing circulatory arrest, shock or refractory hypoxemia and pulmonary embolism with refractory shock. Severe trauma, foreign body obstruction, hypothermia and near drowning are situations in which patients may potentially benefit from ECLS. Early stabilization in the ED can provide a time window for a diagnostic workup and/or urgent procedures, including percutaneous coronary intervention, rewarming or damage control surgery in trauma. The use of ECLS is resource intensive and can be associated with a high risk of complications, especially when performed without previous training. Therefore, ECLS should only be used when the underlying problem is potentially reversible, and the resources are available to address the etiology of organ dysfunction. CONCLUSION: Emergent ECLS has a role in the ED for selected indications in the face of life-threatening conditions. ECLS provides a bridge to recovery, definitive therapy, intervention or surgery. ECLS program requires an appropriately trained staff (physicians, nurses and ECLS specialists), equipment resources and logistical planning.
Authors: Jessika Stefanie Kreß; Marc Rüppel; Hendrik Haake; Jürgen Vom Dahl; Sebastian Bergrath Journal: Anaesthesist Date: 2021-04-08 Impact factor: 1.041
Authors: Justyna Swol; Daniel Brodie; Anne Willers; Bishoy Zakhary; Joseph Belezzo; Zachary Shinar; Scott D Weingart; Jonathan W Haft; Roberto Lorusso; Giles J Peek Journal: Artif Organs Date: 2021-11-05 Impact factor: 2.663
Authors: Jasmeet Soar; Bernd W Böttiger; Pierre Carli; Keith Couper; Charles D Deakin; Therese Djärv; Carsten Lott; Theresa Olasveengen; Peter Paal; Tommaso Pellis; Gavin D Perkins; Claudio Sandroni; Jerry P Nolan Journal: Notf Rett Med Date: 2021-06-08 Impact factor: 0.826
Authors: Laura J Brattain; Theodore T Pierce; Lars A Gjesteby; Matthew R Johnson; Nancy D DeLosa; Joshua S Werblin; Jay F Gupta; Arinc Ozturk; Xiaohong Wang; Qian Li; Brian A Telfer; Anthony E Samir Journal: Biosensors (Basel) Date: 2021-12-18