Literature DB >> 30335614

Small for gestational age and extremely low birth weight infant outcomes.

Elinor Charles1,2, Katie A Hunt1,2, Christopher Harris1,2, Ann Hickey3, Anne Greenough1,2,3,4.   

Abstract

Background Small for gestational age (SGA) infants are less likely to develop respiratory distress syndrome (RDS), but more likely to develop bronchopulmonary dysplasia (BPD) and have a higher mortality. Our aim was to focus on outcomes of those with a birth weight less than or equal to 750 g. Methods The mortality, BPD severity, necrotising enterocolitis (NEC), home oxygen requirement and length of hospital stay were determined according to SGA status of all eligible infants in a 5-year period admitted within the first 24 h after birth. Results The outcomes of 84 infants were assessed, and 35 (42%) were SGA. The SGA infants were more mature (P<0.001), had a lower birth weight centile (P<0.001) and a greater proportion exposed to antenatal corticosteroids (P=0.022). Adjusted for gestational age (GA), there was no significant difference in mortality between the two groups (P=0.242), but a greater proportion of the SGA infants developed severe BPD (P=0.025). The SGA infants had a lower weight z-score at discharge (-3.64 vs. -1.66) (P=0.001), but a decrease in z-score from birth to discharge was observed in both groups (median -1.53 vs. -1.07, P=0.256). Conclusion Despite being more mature, the SGA infants had a similar mortality rate and a greater proportion developed severe BPD.

Entities:  

Keywords:  bronchopulmonary dysplasia; extremely low birth weight; necrotising enterocolitis; small for gestational age

Mesh:

Year:  2019        PMID: 30335614     DOI: 10.1515/jpm-2018-0295

Source DB:  PubMed          Journal:  J Perinat Med        ISSN: 0300-5577            Impact factor:   1.901


  3 in total

1.  [Sex differences in clinical outcomes of extremely preterm infants/extremely low birth weight infants: a propensity score matching study].

Authors:  Zhi-Wen Su; Li-Li Lin; Bi-Jun Shi; Xiao-Xia Huang; Jian-Wei Wei; Chun-Hong Jia; Fan Wu; Qi-Liang Cui
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2022-05-15

2.  Morbidity and mortality in small for gestational age very preterm infants in a middle-income country.

Authors:  Marcia Mangiza; Danielle E Y Ehret; Erika M Edwards; Natasha Rhoda; Lloyd Tooke
Journal:  Front Pediatr       Date:  2022-08-09       Impact factor: 3.569

3.  Respiratory distress in small for gestational age infants based on local newborn curve prior to hospital discharge.

Authors:  Ekawaty Lutfia Haksari; Mohammad Hakimi; Djauhar Ismail
Journal:  Front Pediatr       Date:  2022-09-30       Impact factor: 3.569

  3 in total

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