Literature DB >> 3033516

Highly potent and selective ligands for histamine H3-receptors.

J M Arrang, M Garbarg, J C Lancelot, J M Lecomte, H Pollard, M Robba, W Schunack, J C Schwartz.   

Abstract

New drugs selective for histamine H3-receptors can be used to establish that these receptors are involved in the feedback control of histamine synthesis and release, and to demonstrate their distribution in the brain and peripheral tissues. These drugs provide new tools for affecting physiological and possibly pathological conditions in which histamine is involved.

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Year:  1987        PMID： 3033516     DOI： 10.1038/327117a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  159 in total

1.  Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.

Authors:  X Ligneau; S Morisset; J Tardivel-Lacombe; F Gbahou; C R Ganellin; H Stark; W Schunack; J C Schwartz; J M Arrang
Journal:  Br J Pharmacol       Date:  2000-12       Impact factor: 8.739

2.  Protean agonism at histamine H3 receptors in vitro and in vivo.

Authors:  Florence Gbahou; Agnès Rouleau; Séverine Morisset; Régis Parmentier; Sylvain Crochet; Jian-Sheng Lin; Xavier Ligneau; Joël Tardivel-Lacombe; Holger Stark; Walter Schunack; C Robin Ganellin; Jean-Charles Schwartz; Jean-Michel Arrang
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-05       Impact factor: 11.205

Review 3.  Histamine receptors in the central nervous system.

Authors:  H Timmerman
Journal:  Pharm Weekbl Sci       Date:  1989-10-20

Review 4.  Plenary lecture. A third histamine receptor subtype: characterisation, localisation and functions of the H3-receptor.

Authors:  J C Schwartz; J M Arrang; M Garbarg; H Pollard
Journal:  Agents Actions       Date:  1990-04

5.  Presynaptic histamine H2 receptors modulate the sympathetic nerve transmission in the isolated rat vas deferens; no role for H3-receptors.

Authors:  E Poli; S Todorov; C Pozzoli; G Bertaccini
Journal:  Agents Actions       Date:  1994-10

6.  Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H2-receptors.

Authors:  R Burde; R Seifert; A Buschauer; G Schultz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1989-12       Impact factor: 3.000

7.  Central endogenous histamine modulates sympathetic outflow through H3 receptors in the conscious rabbit.

Authors:  Julian Charles; James A Angus; Christine E Wright
Journal:  Br J Pharmacol       Date:  2003-07       Impact factor: 8.739

8.  Role of histamine in rodent antinociception.

Authors:  P Malmberg-Aiello; C Lamberti; C Ghelardini; A Giotti; A Bartolini
Journal:  Br J Pharmacol       Date:  1994-04       Impact factor: 8.739

9.  Intermediate affinity and potency of clozapine and low affinity of other neuroleptics and of antidepressants at H3 receptors.

Authors:  M Kathmann; E Schlicker; M Göthert
Journal:  Psychopharmacology (Berl)       Date:  1994-12       Impact factor: 4.530

10.  Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, potentiates neurochemical and behavioral effects of haloperidol in the rat.

Authors:  Catherine Pillot; Jordi Ortiz; Anne Héron; Sophie Ridray; Jean-Charles Schwartz; Jean-Michel Arrang
Journal:  J Neurosci       Date:  2002-08-15       Impact factor: 6.167
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